Determinants and implications of mRNA poly (A) tail size–does this protein make my tail look big?

AL Jalkanen, SJ Coleman, J Wilusz - Seminars in cell & developmental …, 2014 - Elsevier
While the phenomenon of polyadenylation has been well-studied, the dynamics of poly (A)
tail size and its impact on transcript function and cell biology are less well-appreciated. The …

Translational control of cell growth and malignancy by the CPEBs

A D'ambrogio, K Nagaoka, JD Richter - Nature Reviews Cancer, 2013 - nature.com
The cytoplasmic polyadenylation element binding proteins (CPEBs) associate with specific
sequences in mRNA 3′ untranslated regions to promote translation. They do so by …

circTAIL-seq, a targeted method for deep analysis of RNA 3′ tails, reveals transcript-specific differences by multiple metrics

VH Gazestani, M Hampton, JE Abrahante, R Salavati… - RNA, 2016 - rnajournal.cshlp.org
Post-transcriptionally added RNA 3′ nucleotide extensions, or tails, impose numerous
regulatory effects on RNAs, including effects on RNA turnover and translation. However …

PAT-Seq: a method for simultaneous quantitation of gene expression, poly (A)-site selection and poly (A)-length distribution in yeast transcriptomes

A Swaminathan, PF Harrison, T Preiss… - Yeast Systems Biology …, 2019 - Springer
Next-generation sequencing (NGS) and its application to RNA (RNA-seq) has opened up
multiple aspects of RNA processing to deep transcriptome-wide analysis at nucleotide …

Structural and biochemical investigation of the Pan2-Pan3 deadenylase complex

TLT Tang - 2020 - repository.cam.ac.uk
Almost all mature eukaryotic mRNAs contain a 3′ polyadenosine (poly (A)) tail, which
promotes nuclear export of mRNAs, protects transcripts from exonucleolytic decay, and …

Revealing the architecture of post transcriptional gene regulatory circuits in trypanosomatids

V Hajihoseini Gazestani - 2017 - escholarship.mcgill.ca
The highly diverged trypanosomatid parasites cause devastating diseases in humans and
animals and continue to pose a major challenge in the drug development. During …

[图书][B] Revealing the architecture of post transcriptional gene regulatory circuits in Trypanosomatids

VH Gazestani - 2016 - search.proquest.com
The highly diverged trypanosomatid parasites cause devastating diseases in humans and
animals and continue to pose a major challenge in the drug development. During …

Generation of Export-Competent mRNPs

S Soucek - 2012 - search.proquest.com
Nuclear export of mRNA is the culmination of the nuclear phase of the gene expression
pathway and appears to be mediated by a Brownian ratchet mechanism that involves three …