Neural crest (NC) cells were described for the first time in 1868 by Wilhelm His. Since then,
this amazing population of migratory stem cells has been intensively studied. It took a …

Exposure to environmental teratogenic pollutant leads to severe birth defects. However, the
biological events underlying these developmental abnormalities remain undefined. Here …

Increasing evidence suggests that cancer cells highjack developmental programs for
disease initiation and progression. Melanoma arises from melanocytes that originate during …

Neuroblastoma is a neural crest-derived embryonal malignancy, which accounts for 13% of
all pediatric cancer mortality, primarily due to tumor recurrence. Therapy-resistant cancer …

The neural crest (NC) represents multipotent cells that arise at the interphase between
ectoderm and prospective epidermis of the neurulating embryo. The NC has major clinical …

Simple Summary Transforming growth factor-beta (TGFβ) mediates various biological
processes including cell growth, cell death, cellular differentiation and stemness, among …

A wide array of neural and non‐neural cell types arises from the neural crest during
vertebrate embryogenesis. The neural crest forms transiently in the dorsal neural …

The neural crest is the name given to the strip of cells at the junction between neural and
epidermal ectoderm in neurula‐stage vertebrate embryos, which is later brought to the …

Developmental neurotoxicity (DNT) is an important endpoint for the safety assessment of
chemicals. However, the current in vivo animal model for DNT assessment is resource …

Exposure to cigarette smoke represents the largest source of preventable death and disease
in the United States. This may be in part due to the nature of the delayed harmful effects as …