[HTML][HTML] Evolution of Toll-like receptor 7/8 agonist therapeutics and their delivery approaches: From antiviral formulations to vaccine adjuvants

S Bhagchandani, JA Johnson, DJ Irvine - Advanced drug delivery reviews, 2021 - Elsevier
Imidazoquinoline derivatives (IMDs) and related compounds function as synthetic agonists
of Toll-like receptors 7 and 8 (TLR7/8) and one is FDA approved for topical antiviral and skin …

[HTML][HTML] Genital warts: a comprehensive review

VR Yanofsky, RV Patel… - The Journal of clinical and …, 2012 - ncbi.nlm.nih.gov
External genital warts, also known as condylomata acuminata, are extremely common, with
between 500,000 to one million new cases diagnosed each year in the United States alone …

[HTML][HTML] Evolving role of immunotherapy in the treatment of refractory warts

DM Thappa, MJ Chiramel - Indian dermatology online journal, 2016 - journals.lww.com
Cutaneous and genital warts are common dermatological conditions caused by the human
papilloma virus (HPV). Although it is a benign condition, it causes disfigurement, has a …

[图书][B] Pediatric Dermatology: Expert Consult-Online and Print, 2-Volume Set

LA Schachner, RC Hansen - 2011 - books.google.com
The latest edition of Pediatric Dermatology, edited by Lawrence A. Schachner, MD and
Ronald C. Hansen, MD brings you the detailed guidance you need to effectively diagnose …

Review of squamous premalignant vulvar lesions

HP Van de Nieuwenhof, IAM Van der Avoort… - Critical reviews in …, 2008 - Elsevier
Vulvar squamous cell carcinoma (SCC) develops following two different pathways, which
have their own premalignant lesions. In the absence of human papilloma virus (HPV), vulvar …

Imiquimod and resiquimod as novel immunomodulators

DH Dockrell, GR Kinghorn - Journal of Antimicrobial …, 2001 - academic.oup.com
Augmenting the host's natural immune response to viruses by the administration of
exogenous cytokines such as interferon-α (IFN-α) is a strategy increasingly employed in …

Efficacy of intralesional immunotherapy for the treatment of warts: A review of the literature

AS Aldahan, S Mlacker, VV Shah, P Kamath… - Dermatologic …, 2016 - Wiley Online Library
Warts are common epidermal growths caused by human papillomavirus that often cause
significant discomfort and embarrassment. Current treatment options include topical …

Formulation and preclinical evaluation of a toll-like receptor 7/8 agonist as an anti-tumoral immunomodulator

R Lu, C Groer, PA Kleindl, KR Moulder, A Huang… - Journal of controlled …, 2019 - Elsevier
The toll-like receptor 7 and 8 (TLR7/8) agonist Resiquimod (R848) has been recognized as
a promising immunostimulator for the treatment of cutaneous cancers in multiple clinical …

咪喹莫特乳膏治疗尖锐湿疣随机, 双盲, 多中心研究

顾恒, 曾凡钦, 郭在培, 彭振辉, 毕志刚, 朱学骏, 陈昆… - 中华皮肤科杂志, 2003 - cqvip.com
目的了解5% 咪喹莫特乳膏治疗肛周和外生殖器尖锐湿疣的临床疗效和安全性. 方法采用随机,
双盲, 平行对照的临床研究方法, 受试者每周3 次外搽研究药物, 疗程8 周. 疣体完全消退者继续 …

If small molecules immunotherapy comes, can the prime be far behind?

J Zhang, Y Zhang, B Qu, H Yang, S Hu… - European Journal of …, 2021 - Elsevier
Anti-cancer immunotherapy, which includes cellular immunotherapy, immune checkpoint
inhibitors and cancer vaccines, has transformed the treatment strategies of several …