Although Zika virus (ZIKV) infection is often asymptomatic, in some cases, it can lead to birth
defects in newborns or serious neurologic complications in adults. However, little is known …

Zika virus is the latest addition to an ever-growing list of arboviruses that are causing
outbreaks with serious consequences. A few mild cases were recorded between 1960 and …

Zika virus is a re-emerging flavivirus transmitted primarily by arthropod vectors. The recent
devastating outbreak of Zika virus in Brazil was preceded by the slow global encroachment …

Urgent treatments, in any modality, to fight SARS-CoV-2 infections are desired by society in
general, by health professionals, by Estate-leaders and, mainly, by the scientific community …

Background The combination of sofosbuvir and daclatasvir has a well-established safety
profile and improves clinical outcomes in HCV patients. In silico and in vitro studies suggest …

Nucleos (t) ide analogues play pivotal roles as antiviral, cytotoxic or immunosuppressive
agents. Here, we review recent reports of nucleoside analogues that exhibit broad-spectrum …

Introduction and objectives Direct antiviral agents (DAAs) are very efficient in inhibiting
hepatitis C virus and might be used to treat infections caused by other flaviviruses whose …

A strong correlation between Zika virus (ZIKV) infection and severe neurological disease in
newborns and occasionally adults has emerged in the Brazilian outbreak. Efficient human …

Zika virus (ZIKV) is an arbovirus transmitted mainly by mosquitos of Aedes species. The
virus has emerged in recent years and spread throughout North and South Americas. The …

In the year 2015, new Zika virus (ZIKV) broke out in Brazil and spread away in more than 80
countries. Scientists directed their efforts toward viral polymerase in attempt to find inhibitors …