Red Light-Mediated Photoredox Catalysis Triggers Nitric Oxide Release for Treatment of Cutibacterium Acne Induced Intervertebral Disc Degeneration
S Tao, Z Shen, J Chen, Z Shan, B Huang, X Zhang… - ACS …, 2022 - ACS Publications
Intervertebral disc degeneration (IVDD) has been known as a highly prevalent and disabling
disease, which is one of the main causes of low back pain and disability. Unfortunately …
disease, which is one of the main causes of low back pain and disability. Unfortunately …
[HTML][HTML] The bacteria-positive proportion in the disc tissue samples from surgery: a systematic review and meta-analysis
Y Jiao, Y Lin, Y Zheng, Y Yuan, Z Chen, P Cao - European Spine Journal, 2019 - Springer
Purpose The role of bacteria, especially Propionibacterium acnes (P. acnes), in human
intervertebral disc diseases has raised attention in recent years. However, limited sample …
intervertebral disc diseases has raised attention in recent years. However, limited sample …
Cutibacterium acnes in spine pathology: pathophysiology, diagnosis, and management
JG Khalil, SD Gandhi, DK Park… - JAAOS-Journal of the …, 2019 - journals.lww.com
Cutibacterium acnes, long thought to be skin flora of pathological insignificance, has seen a
surge in interest for its role in spine pathology. C acnes has been identified as a pathogen in …
surge in interest for its role in spine pathology. C acnes has been identified as a pathogen in …
Cutibacterium acnes is an intracellular and intra-articular commensal of the human shoulder joint
R Hudek, A Brobeil, H Brüggemann, F Sommer… - Journal of shoulder and …, 2021 - Elsevier
Background Cutibacterium acnes (C acnes) is a mysterious member of the shoulder
microbiome and is associated with chronic postoperative complications and low-grade …
microbiome and is associated with chronic postoperative complications and low-grade …
Damage to the human lumbar cartilage endplate and its clinical implications
B Huang, J Liu, X Wei, S Li, Y Xiang, H Wu… - Journal of …, 2021 - Wiley Online Library
The cartilaginous endplate (CEP) is a thin layer of hyaline cartilage, and plays an important
role in the diffusion of nutrients into the intervertebral discs. Its damage may seriously affect …
role in the diffusion of nutrients into the intervertebral discs. Its damage may seriously affect …
Osteal tissue macrophages are involved in endplate osteosclerosis through the OSM-STAT3/YAP1 signaling axis in modic changes
J Wang, Z Zheng, B Huang, H Wu, X Zhang… - The Journal of …, 2020 - journals.aai.org
Modic changes (MCs) are radiographic manifestations of lumbar degenerative diseases.
Various types of MCs are often associated with endplate osteosclerosis. Osteal tissue …
Various types of MCs are often associated with endplate osteosclerosis. Osteal tissue …
Low virulence bacterial infections in cervical intervertebral discs: a prospective case series
Y Chen, X Wang, X Zhang, H Ren, B Huang… - European Spine …, 2018 - Springer
Study design A prospective cross-sectional case series study. Objective To investigate the
prevalence of low virulence disc infection and its associations with characteristics of patients …
prevalence of low virulence disc infection and its associations with characteristics of patients …
[HTML][HTML] Different phylotypes of Cutibacterium acnes cause different modic changes in intervertebral disc degeneration
W Lan, X Wang, X Tu, X Hu, H Lu - PloS one, 2022 - journals.plos.org
Background The contribution of Cutibacterium acnes (C. acnes) infection to intervertebral
disc degeneration (IDD) and the antibiotic therapy has evoked several controversies in …
disc degeneration (IDD) and the antibiotic therapy has evoked several controversies in …
Propionibacterium acnes incubation in the discs can result in time-dependent modic changes: A long-term rabbit model
Z Shan, X Zhang, S Li, T Yu, J Liu, F Zhao - Spine, 2017 - journals.lww.com
Study Design. A case-control study of animal model of Modic changes (MCs) on rabbits.
Objective. To evaluate the feasibility of inducing of MCs by injection of Propionibacterium …
Objective. To evaluate the feasibility of inducing of MCs by injection of Propionibacterium …
The therapeutic effect of tanshinone IIA on Propionibacterium acnes‐induced inflammation in vitro
Y Li, Y Zhou - Dermatologic therapy, 2018 - Wiley Online Library
Acne vulgaris, a chronic inflammatory skin disease, affects many adolescents. New
therapeutic agents for acne allow for a higher therapeutic activity, but fewer side effects …
therapeutic agents for acne allow for a higher therapeutic activity, but fewer side effects …