Flavonoids as therapeutic candidates for emotional disorders such as anxiety and depression

YH Ko, SK Kim, SY Lee, CG Jang - Archives of pharmacal research, 2020 - Springer
Emotional disorders such as anxiety and depression are widespread psychological
diseases that affect up to 20% of the world's population. There are many approaches to the …

Quercetin abates aluminum trioxide nanoparticles and lead acetate induced altered sperm quality, testicular oxidative damage, and sexual hormones disruption in …

A Behairy, MM Hashem, K Abo-El-Sooud… - Antioxidants, 2022 - mdpi.com
This study examined the effects of exposure to lead acetate (PbAc) and/or aluminum trioxide
nanoparticles (Al2O3NPs) on testicular function. Additionally, the probable reproprotective …

Cadmium-induced apoptosis through reactive oxygen species-mediated mitochondrial oxidative stress and the JNK signaling pathway in TM3 cells, a model of mouse …

S Wang, X Ren, X Hu, L Zhou, C Zhang… - Toxicology and applied …, 2019 - Elsevier
Cadmium (Cd) is a heavy metal that widely exists in the environment and industry, and
which causes serious damages to reproductive system. Recent studies have reported that …

The role of medicinal plants and natural products in melioration of cadmium toxicity

S Bhattacharya - Oriental Pharmacy and Experimental Medicine, 2018 - Springer
Cadmium is extremely toxic heavy metal and there is no specific, safe and efficacious
therapeutic management of cadmium toxicity. Scientific literature reveals several medicinal …

Effect of quercetin on cadmium chloride‐induced impairments in sexual behaviour and steroidogenesis in male Wistar rats

GA Ujah, VU Nna, MI Agah, LO Omue, CB Leku… - Andrologia, 2018 - Wiley Online Library
Cadmium chloride (CdCl2) has been reported to cause reproductive toxicity in male rats,
mainly through oxidative stress. This study examined its effect on sexual behaviour, as one …

[HTML][HTML] Quercetin ameliorates testosterone secretion disorder by inhibiting endoplasmic reticulum stress through the miR-1306-5p/HSD17B7 axis in diabetic rats

D Wang, Y Li, Q Zhai, Y Zhu, B Liu… - Bosnian journal of basic …, 2022 - ncbi.nlm.nih.gov
Testicular damage and testosterone secretion disorder are associated with diabetes
mellitus. Quercetin, a common flavonoid, has antioxidant, anti-cancer, and blood sugar …

Effect of cadmium administration on the antioxidant system and neuronal death in the hippocampus of rats

S Treviño, G Pulido, E Fuentes, A Handal‐Silva… - Synapse, 2022 - Wiley Online Library
Cadmium (Cd) is a heavy metal classified as a carcinogen whose exposure could affect the
function of the central nervous system. Studies suggest that Cd modifies neuronal …

Protective effects of quercetin supplementation against short-term toxicity of cadmium-induced hematological impairment, hypothyroidism, and testicular disturbances …

GM Badr, H Elsawy, A Sedky, R Eid, A Ali… - … Science and Pollution …, 2019 - Springer
The aim of this study was to evaluate the probable protective effect of quercetin (QUE)
against cadmium (Cd)-induced sub-chronic toxicity in rats. Adult male rats were given either …

Protective mechanism of sulforaphane on cadmium-induced sertoli cell injury in mice testis via Nrf2/ARE signaling pathway

SH Yang, LH Yu, L Li, Y Guo, Y Zhang, M Long, P Li… - Molecules, 2018 - mdpi.com
The present study evaluated the mechanism underlying the protective effect of sulforaphane
(SFN) on cadmium (Cd)-induced Sertoli cell (TM4 cells) injury in mice. The apoptosis rate of …

Protective effect of Lycium barbarum polysaccharides against cadmium-induced testicular toxicity in male mice

L Zhang, Q Li, G Zheng, Y Chen, M Huang, L Zhang… - Food & function, 2017 - pubs.rsc.org
The present study was performed to determine whether Lycium barbarum polysaccharides
(LBPs) would protect mice against cadmium (Cd)-induced testicular toxicity. Seventy-two …