Permeation enhancers in transdermal drug delivery: Benefits and limitations
A Kováčik, M Kopečná, K Vávrová - Expert opinion on drug delivery, 2020 - Taylor & Francis
Introduction: Transdermal drug delivery has several clinical benefits over conventional
routes of drug administration. To open the transdermal route for a wider range of drugs …
routes of drug administration. To open the transdermal route for a wider range of drugs …
[HTML][HTML] Improved topical drug delivery: Role of permeation enhancers and advanced approaches
The delivery of drugs via transdermal routes is an attractive approach due to ease of
administration, bypassing of the first-pass metabolism, and the large skin surface area …
administration, bypassing of the first-pass metabolism, and the large skin surface area …
[HTML][HTML] Chitosan-coated 5-fluorouracil incorporated emulsions as transdermal drug delivery matrices
The purpose of the present study was to develop emulsions encapsulated by chitosan on
the outer surface of a nano droplet containing 5-fluorouracil (5-FU) as a model drug. The …
the outer surface of a nano droplet containing 5-fluorouracil (5-FU) as a model drug. The …
[HTML][HTML] Methylene blue-loaded niosome: preparation, physicochemical characterization, and in vivo wound healing assessment
Following skin injury, the overproduction of reactive oxygen species (ROS) during the
inflammatory phase can cause tissue damage and delay in wound healing. Methylene blue …
inflammatory phase can cause tissue damage and delay in wound healing. Methylene blue …
Transdermal drug delivery
Transdermal drug delivery systems (TDDS), also known as “'patches,”'are dosage forms that
provide a controlled release of therapeutically effective amount of drug across a patient's …
provide a controlled release of therapeutically effective amount of drug across a patient's …
[HTML][HTML] Regulatory status quo and prospects for biosurfactants in pharmaceutical applications
The concept of going 'green'and 'cold'has led to utilizing renewable resources for the
synthesis of microbial biosurfactants that are both patient and eco-friendly. In this review, we …
synthesis of microbial biosurfactants that are both patient and eco-friendly. In this review, we …
[HTML][HTML] CPE-DB: An open database of chemical penetration enhancers
The cutaneous delivery route currently accounts for almost 10% of all administered drugs
and it is becoming more common. Chemical penetration enhancers (CPEs) increase the …
and it is becoming more common. Chemical penetration enhancers (CPEs) increase the …
[HTML][HTML] In vitro release, mucosal permeation and deposition of cannabidiol from liquisolid systems: The influence of liquid vehicles
This work investigated the influence of liquid vehicles on the release, mucosal permeation
and deposition of cannabidiol (CBD) from liquisolid systems. Various vehicles, including …
and deposition of cannabidiol (CBD) from liquisolid systems. Various vehicles, including …
Niacinamide: a review on dermal delivery strategies and clinical evidence
RR Ong, CF Goh - Drug Delivery and Translational Research, 2024 - Springer
Niacinamide, an active form of vitamin B3, is recognised for its significant dermal benefits
including skin brightening, anti-ageing properties and the protection of the skin barrier. Its …
including skin brightening, anti-ageing properties and the protection of the skin barrier. Its …
Tailoring novel soft nano-vesicles 'Flexosomes' for enhanced transdermal drug delivery: Optimization, characterization and comprehensive ex vivo–in vivo evaluation
HA Abdel-Messih, RAH Ishak, AS Geneidi… - International journal of …, 2019 - Elsevier
The transdermal route is a convenient non-invasive way for drug delivery, however, the
hydrophobic compact nature of stratum corneum (SC) forms an obstacle hindering the …
hydrophobic compact nature of stratum corneum (SC) forms an obstacle hindering the …