Inhaled corticosteroids in COPD: friend or foe?

A Agusti, LM Fabbri, D Singh, J Vestbo… - European …, 2018 - Eur Respiratory Soc
The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the treatment of
patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can …

Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management

PG Woodruff, A Agusti, N Roche, D Singh, FJ Martinez - The Lancet, 2015 - thelancet.com
Chronic obstructive pulmonary disease (COPD) is a common, complex, and heterogeneous
disorder that is responsible for substantial and growing morbidity, mortality, and health-care …

Long-term triple therapy de-escalation to indacaterol/glycopyrronium in patients with chronic obstructive pulmonary disease (SUNSET): a randomized, double-blind …

KR Chapman, JR Hurst, SM Frent, M Larbig… - American journal of …, 2018 - atsjournals.org
Rationale: There are no studies on withdrawal of inhaled corticosteroids in patients on long-
term triple therapy in the absence of frequent exacerbations. Objectives: To evaluate the …

Withdrawal of inhaled corticosteroids in COPD: a European Respiratory Society guideline

JD Chalmers, IF Laska, FME Franssen… - European …, 2020 - Eur Respiratory Soc
Inhaled corticosteroids (ICS) combined with bronchodilators can reduce the frequency of
exacerbations in some patients with chronic obstructive pulmonary disease (COPD). There …

Guía española de la enfermedad pulmonar obstructiva crónica (GesEPOC) 2017. Tratamiento farmacológico en fase estable

M Miravitlles, JJ Soler-Cataluña, M Calle… - Archivos de …, 2017 - Elsevier
La enfermedad pulmonar obstructiva crónica (EPOC) presenta una gran heterogeneidad
clínica, por lo que su tratamiento se debe individualizar según el nivel de riesgo y el …

Dual combination therapy versus long‐acting bronchodilators alone for chronic obstructive pulmonary disease (COPD): a systematic review and network meta …

Y Oba, E Keeney, N Ghatehorde… - Cochrane Database of …, 2018 - cochranelibrary.com
Background Long‐acting bronchodilators such as long‐acting β‐agonist (LABA), long‐
acting muscarinic antagonist (LAMA), and LABA/inhaled corticosteroid (ICS) combinations …

The inevitable drift to triple therapy in COPD: an analysis of prescribing pathways in the UK

G Brusselle, D Price, K Gruffydd-Jones… - … journal of chronic …, 2015 - Taylor & Francis
Background Real-world prescription pathways leading to triple therapy (TT)(inhaled
corticosteroid [ICS] plus long-acting β2-agonist bronchodilator [LABA] plus long-acting …

[HTML][HTML] “Trying, but failing”—the role of inhaler technique and mode of delivery in respiratory medication adherence

F Braido, H Chrystyn, I Baiardini… - The Journal of Allergy …, 2016 - Elsevier
Inhaled therapies are the backbone of asthma and chronic obstructive pulmonary disease
management, helping to target therapy at the airways. Adherence to prescribed treatment is …

Withdrawal of inhaled corticosteroids can be safe in COPD patients at low risk of exacerbation: a real-life study on the appropriateness of treatment in moderate COPD …

A Rossi, M Guerriero, A Corrado - Respiratory research, 2014 - Springer
Background It has been suggested that withdrawal of inhaled corticosteroids (ICS) in COPD
patients on maintenance treatment results in deterioration of symptoms, lung function and …

Inhaled corticosteroids and the pneumonia risk in patients with chronic obstructive pulmonary disease: a meta-analysis of randomized controlled trials

H Chen, J Sun, Q Huang, Y Liu, M Yuan… - Frontiers in …, 2021 - frontiersin.org
Background: Whether all types of inhaled corticosteroids (ICSs) would increase the
pneumonia risk in patients with chronic obstructive pulmonary disease (COPD) remains …