HIV type 2 (HIV-2), a closely related retrovirus discovered a few years after HIV type 1,
causes AIDS in only a minority of infected individuals. Determining why HIV-2 causes …

Background Progressive immune dysfunction and the acquired immunodeficiency syndrome
(AIDS) develop in most persons with untreated infection with human immunodeficiency virus …

Background. The efficacy of various antiretroviral (ARV) therapy regimens for human
immunodeficiency virus type 2 (HIV-2) infection remains unclear. HIV-2 is intrinsically …

Compared with human immunodeficiency virus type 1 (HIV-1), little is known about the
susceptibility of HIV-2 to antibody neutralization. We characterized the potency and breadth …

Background. Antibody cross-reactivity complicates differential diagnosis of human
immunodeficiency virus (HIV) type 2 (HIV-2) using standard serologic screening and …

Objective: To compare survival times of HIV-1 single and HIV-1 and HIV-2 dual-infected
individuals. Design: Prospective open cohort study. Methods: We analysed data from 259 …

HIV-1 and HIV-2 are two related retroviruses and, in regions where both infections are
endemic, HIV-1/2 dual infection can occur. Several important questions arise about the …

The functional capacities of CD8+ T cells important for virus clearance are influenced by
interactions with antigen presenting cells (APCs) and CD4+ T cells during initial selection …

Objective: Dual infection with HIV-1 and HIV-2, which is not uncommon in West Africa, has
implications for transmission, progression, and antiretroviral therapy (ART). Few studies …

Background: Human gammadelta (γδ) T cells play an important role in protective immunity in
HIV-1 and simian immunodeficiency virus infection; their role in HIV-2 infection is unknown …