[HTML][HTML] NSUN2-mediated RNA 5-methylcytosine promotes esophageal squamous cell carcinoma progression via LIN28B-dependent GRB2 mRNA stabilization

J Su, G Wu, Y Ye, J Zhang, L Zeng, X Huang, Y Zheng… - Oncogene, 2021 - nature.com
Methylcytosine (m5C) is a posttranscriptional RNA modification participating in many critical
bioprocesses, but its functions in human cancer remain unclear. Here, by detecting the …

STAT3β disrupted mitochondrial electron transport chain enhances chemosensitivity by inducing pyroptosis in esophageal squamous cell carcinoma

ZY Zheng, PL Yang, RY Li, LX Liu, XE Xu, LD Liao, X Li… - Cancer letters, 2021 - Elsevier
The clinical efficacy of cisplatin in the treatment of esophageal squamous cell carcinoma
(ESCC) is undesirable. Signal transducer and activator of transcription 3β (STAT3β), a splice …

MTA1, a novel ATP synthase complex modulator, enhances colon cancer liver metastasis by driving mitochondrial metabolism reprogramming

T Wang, F Sun, C Li, P Nan, Y Song, X Wan… - Advanced …, 2023 - Wiley Online Library
Liver metastasis is the most fatal event of colon cancer patients. Warburg effect has been
long challenged by the fact of upregulated oxidative phosphorylation (OXPHOS), while its …

[HTML][HTML] Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma

ZY Zheng, MY Chu, W Lin, YQ Zheng, XE Xu… - Cell Death & …, 2022 - nature.com
Esophageal squamous cell carcinoma (ESCC) is one of the world's leading causes of death,
and its primary clinical therapy relies on surgical resection, chemotherapy, radiotherapy, and …

[HTML][HTML] Patient-derived xenograft: a developing tool for screening biomarkers and potential therapeutic targets for human esophageal cancers

T Lan, X Xue, LC Dunmall, J Miao, Y Wang - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Esophageal cancer (EC) represents a human malignancy, diagnosed often at the advanced
stage of cancer and resulting in high morbidity and mortality. The development of precision …

Daurisoline suppresses esophageal squamous cell carcinoma growth in vitro and in vivo by targeting MEK1/2 kinase

D Wang, W Zhang, X Zhang, M Li, Q Wu… - Molecular …, 2023 - Wiley Online Library
Esophageal squamous cell carcinoma (ESCC) accounts for 90% of esophageal cancers
and has a high mortality rate worldwide. The 5‐year survival rate of ESCC patients in …

[HTML][HTML] Upregulation of MTA1 in Colon Cancer Drives A CD8+ T Cell-Rich But Classical Macrophage-Lacking Immunosuppressive Tumor Microenvironment

Y Zhou, P Nan, C Li, H Mo, Y Zhang, H Wang… - Frontiers in …, 2022 - frontiersin.org
Background The MTA1 protein encoded by metastasis-associated protein 1 (MTA1) is a key
component of the ATP-dependent nucleosome remodeling and deacetylase (NuRD) …

Sox2 induces tumorigenesis and angiogenesis of early-stage esophageal squamous cell carcinoma through secretion of Suprabasin

K Takahashi, N Asano, A Imatani, Y Kondo… - …, 2020 - academic.oup.com
Early stage of esophageal squamous cell carcinoma (ESCC) is known to be accompanied
by angiogenesis and morphological changes of microvessels. Transcription factor Sox2 is …

LINC00963 functions as an oncogene in bladder cancer by regulating the miR-766-3p/MTA1 axis

N Zhou, X Zhu, L Man - Cancer Management and Research, 2020 - Taylor & Francis
Purpose Long non-coding RNAs have been found to be involved in bladder cancer
development. This article studied LINC00963 effects on bladder cancer progression to …

[HTML][HTML] Screening and verification of hub genes in esophageal squamous cell carcinoma by integrated analysis

H Wu, P Zhu, P Shu, S Zhang - Scientific Reports, 2024 - nature.com
Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant
tumors. However, the mechanisms underlying ESCC tumorigenesis have not been fully …