Although most patients recover from acute COVID-19, some experience postacute sequelae
of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of …

Nitric oxide (NO), generated from L-arginine and oxygen by NO synthases, is a pleiotropic
signaling molecule involved in cardiovascular and metabolic regulation. More recently, an …

Background Vascular dysfunction is a precursor to the atherosclerotic cascade, significantly
increasing susceptibility to cardiovascular events such as myocardial infarction or stroke …

Nitric oxide (NO) is a key signalling molecule in the cardiovascular, immune and central
nervous systems, and crucial steps in the regulation of NO bioavailability in health and …

The occurrence of heavy metals in soils may be beneficial or toxic to the environment. The
biota may require some of these elements considered essentials (like Fe, Zn, Cu or Mo) in …

Reactive oxygen species (ROS) are a family of molecules that are continuously generated,
transformed and consumed in all living organisms as a consequence of aerobic life. The …

The inorganic anions nitrate (NO3−) and nitrite (NO2−) were previously thought to be inert
end products of endogenous nitric oxide (NO) metabolism. However, recent studies show …

Oxidative stress (OS), a state characterized by an imbalance between pro-oxidant molecules
including reactive oxygen and nitrogen species, and antioxidant defenses, has been …

Nitric oxide (NO) and reactive oxygen species exert multiple modulating effects on
inflammation and play a key role in the regulation of immune responses. They affect virtually …

Hypoxia and free radicals, such as reactive oxygen and nitrogen species, can alter the
function and/or activity of the transcription factor hypoxia-inducible factor 1 (HIF1). Interplay …