[HTML][HTML] The causal cascade to multiple sclerosis: a model for MS pathogenesis

DS Goodin - PloS one, 2009 - journals.plos.org
Background MS pathogenesis seems to involve both genetic susceptibility and
environmental risk factors. Three sequential factors are implicated in the environmental risk …

[HTML][HTML] Clinical implications of a possible role of vitamin D in multiple sclerosis

C Pierrot-Deseilligny - Journal of neurology, 2009 - Springer
Hypovitaminosis D is currently one of the most studied environmental risk factors for multiple
sclerosis (MS) and is potentially the most promising in terms of new clinical implications …

Is multiple sclerosis an autoimmune disease?

B Wootla, M Eriguchi, M Rodriguez - Autoimmune diseases, 2012 - Wiley Online Library
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) with varied clinical presentations and heterogeneous histopathological …

Vitamin D levels and risk of multiple sclerosis in patients with clinically isolated syndromes

V Martinelli, G Dalla Costa, B Colombo… - Multiple Sclerosis …, 2014 - journals.sagepub.com
Background: Growing evidence suggests that vitamin D deficiency may be one of the most
important environmental factors for the development of multiple sclerosis (MS). Objectives …

The roles of vitamin D and its analogs in inflammatory diseases

Z Lin, W Li - Current topics in medicinal chemistry, 2016 - ingentaconnect.com
The discovery of nonclassical actions, other than mineral homeostasis, of 1α, 25-
dihydroxyvitamin D3 (1, 25D3) has expanded its applications. Among these, its anti …

Monthly ambient sunlight, infections and relapse rates in multiple sclerosis

H Tremlett, IAF Van Der Mei, F Pittas, L Blizzard… - …, 2008 - karger.com
Background: Monthly variation in multiple sclerosis (MS) relapses has been found. The
relationship between seasonal environmental factors, infections, serum vitamin D [25 (OH) …

Contribution of vitamin D insufficiency to the pathogenesis of multiple sclerosis

C Pierrot-Deseilligny… - Therapeutic advances in …, 2013 - journals.sagepub.com
The contribution of vitamin D insufficiency to the pathogenesis of multiple sclerosis (MS) is
reviewed. Among the multiple recently discovered actions of vitamin D, an …

[HTML][HTML] Wellness and the role of comorbidities in multiple sclerosis

BP Moss, MR Rensel, CM Hersh - Neurotherapeutics, 2017 - Elsevier
Multiple sclerosis (MS) is a demyelinating and neurodegenerative disorder of the central
nervous system, for which disease modifying therapies (DMTs) are the mainstay treatment …

The association between serum 25OHD levels and hypothyroid Hashimoto's thyroiditis

N Mansournia, MA Mansournia, S Saeedi… - Journal of …, 2014 - Springer
Background Vitamin D is shown to be a potent immunomodulator. Considering the potential
role of low serum vitamin D levels in autoimmune disorder, we evaluated the association …

An adverse lipid profile and increased levels of adiposity significantly predict clinical course after a first demyelinating event

P Tettey, S Simpson, B Taylor, AL Ponsonby… - Journal of Neurology …, 2017 - jnnp.bmj.com
Objective To investigate the prospective associations between adiposity and lipid-related
variables and conversion to multiple sclerosis (MS), time to subsequent relapse and …