[HTML][HTML] Assessment of apolipoprotein (a) isoform size using phenotypic and genotypic methods

F Fogacci, V Di Micoli, A Avagimyan… - International Journal of …, 2023 - mdpi.com
Apolipoprotein (a)(apo (a)) is the protein component that defines lipoprotein (a)(Lp (a))
particles and is encoded by the LPA gene. The apo (a) is extremely heterogeneous in size …

Comprehensive Analysis of Genomic Variation in the LPA Locus and Its Relationship to Plasma Lipoprotein(a) in South Asians, Chinese, and European Caucasians

MB Lanktree, SS Anand, S Yusuf… - Circulation …, 2010 - Am Heart Assoc
Background—Functional copy number variation in the apolipoprotein (a) gene (LPA)
underlies a variable number of protein kringle domains repeated in tandem in the lipoprotein …

Lipoprotein Lp (a) and atherothrombotic disease

A de la Peña-Dı́az, R Izaguirre-Avila… - Archives of medical …, 2000 - Elsevier
High plasma concentrations of lipoprotein (a)[Lp (a)] are now considered a major risk factor
for atherosclerosis and cardiovascular disease. This effect of Lp (a) may be related to its …

Commutability assessment of candidate reference materials for lipoprotein (a) by comparison of a MS-based candidate reference measurement procedure with …

I Dikaios, H Althaus, E Angles-Cano… - Clinical …, 2023 - academic.oup.com
Background Elevated concentrations of lipoprotein (a)[Lp (a)] are directly related to an
increased risk of cardiovascular diseases, making it a relevant biomarker for clinical risk …

[HTML][HTML] Genome-wide association study of plasma lipoprotein (a) levels identifies multiple genes on chromosome 6q [S]

C Ober, AS Nord, EE Thompson, L Pan, Z Tan… - Journal of lipid …, 2009 - ASBMB
Plasma lipoprotein (a)(Lp [a]) level is an independent risk factor of cardiovascular disease
that is under strong genetic control. We conducted a genome-wide association study of …

Planning continuous-curvature paths for car-like robots

A Scheuer, T Fraichard - Proceedings of IEEE/RSJ International …, 1996 - ieeexplore.ieee.org
This paper presents a continuous-curvature path planner (CCPP) for a car-like robot.
Previous collision-free path planners for car-like robots compute paths made up of straight …

Evidence for several independent genetic variants affecting lipoprotein (a) cholesterol levels

W Lu, YC Cheng, K Chen, H Wang… - Human molecular …, 2015 - academic.oup.com
Abstract Lipoprotein (a)[Lp (a)] is an independent risk factor for atherosclerosis-related
events that is under strong genetic control (heritability= 0.68–0.98). However, causal …

Binding of recombinant apolipoprotein (a) to human platelets and effect on platelet aggregation

C Martínez, J Rivera, S Loyau, J Corral… - Thrombosis and …, 2001 - thieme-connect.com
The interaction of lipoprotein (a)[Lp (a)] with platelets is not well defined, particularly with
regards to the individual contribution of the protein components of Lp (a), the apo B-100 and …

[HTML][HTML] Determination of lipoprotein (a) kringle repeat number from genomic DNA: copy number variation genotyping using qPCR

MB Lanktree, C Rajakumar, JH Brunt… - Journal of lipid …, 2009 - ASBMB
Plasma lipoprotein (a)[Lp (a)] concentration is related to risk of cardiovascular disease. The
defining protein component of Lp (a) particles, apolipoprotein (a)[apo (a)], is encoded by the …

Lp (a) particles mold fibrin-binding properties of apo (a) in size-dependent manner: a study with different-length recombinant apo (a), native Lp (a), and monoclonal …

C Kang, M Dominguez, S Loyau, T Miyata… - … , and vascular biology, 2002 - Am Heart Assoc
Objective—Small-sized apolipoprotein (a)[apo (a)] isoforms with high antifibrinolytic activity
are frequently found in cardiovascular diseases, suggesting a role for apo (a) size in …