Mechanistic insights into the oxidized low‐density lipoprotein‐induced atherosclerosis
Dyslipidaemia has a prominent role in the onset of notorious atherosclerosis, a disease of
medium to large arteries. Atherosclerosis is the prime root of cardiovascular events …
medium to large arteries. Atherosclerosis is the prime root of cardiovascular events …
[HTML][HTML] Oxidative stress, antioxidants and hypertension
M Amponsah-Offeh, P Diaba-Nuhoho, S Speier… - Antioxidants, 2023 - mdpi.com
As a major cause of morbidity and mortality globally, hypertension remains a serious threat
to global public health. Despite the availability of many antihypertensive medications …
to global public health. Despite the availability of many antihypertensive medications …
[HTML][HTML] LOX-1: regulation, signaling and its role in atherosclerosis
Atherosclerosis has long been known to be a chronic inflammatory disease. In addition,
there is intense oxidative stress in atherosclerosis resulting from an imbalance between the …
there is intense oxidative stress in atherosclerosis resulting from an imbalance between the …
Lipid peroxidation in atherosclerotic cardiovascular diseases
E Gianazza, M Brioschi… - Antioxidants & redox …, 2021 - liebertpub.com
Significance: Atherosclerotic cardiovascular diseases (ACVDs) continue to be a primary
cause of mortality worldwide in adults aged 35–70 years, occurring more often in countries …
cause of mortality worldwide in adults aged 35–70 years, occurring more often in countries …
Oleuropein: A natural antioxidant molecule in the treatment of metabolic syndrome
Olive (Olea europaea Linn., Fam. Oleaceae) is commonly known as Zaytoon in
Mediterranean region. Its fruits and oil are essential components of Mediterranean diets …
Mediterranean region. Its fruits and oil are essential components of Mediterranean diets …
Effects of PCSK9 targeting: alleviating oxidation, inflammation, and atherosclerosis
E Punch, J Klein, P Diaba‐Nuhoho… - Journal of the …, 2022 - Am Heart Assoc
Characterized as a chronic inflammatory disease of the large arteries, atherosclerosis is the
primary cause of cardiovascular disease, the leading contributor of morbidity and mortality …
primary cause of cardiovascular disease, the leading contributor of morbidity and mortality …
[HTML][HTML] Atorvastatin ester regulates lipid metabolism in hyperlipidemia rats via the PPAR-signaling pathway and HMGCR expression in the liver
N Hu, C Chen, J Wang, J Huang, D Yao… - International Journal of …, 2021 - mdpi.com
Atorvastatin ester (Ate) is a structural trim of atorvastatin that can regulate hyperlipidemia.
The purpose of this study was to evaluate the lipid-lowering effect of Ate. Male Sprague …
The purpose of this study was to evaluate the lipid-lowering effect of Ate. Male Sprague …
LOX-1 receptor: A potential link in atherosclerosis and cancer
S Balzan, V Lubrano - Life sciences, 2018 - Elsevier
Altered production of reactive oxygen species (ROS), causing lipid peroxidation and DNA
damage, contributes to the progression of atherosclerosis and cancer. Lectin-like oxidized …
damage, contributes to the progression of atherosclerosis and cancer. Lectin-like oxidized …
[HTML][HTML] PCSK9 functions in atherosclerosis are not limited to plasmatic LDL-cholesterol regulation
A Luquero, L Badimon, M Borrell-Pages - Frontiers in Cardiovascular …, 2021 - frontiersin.org
The relevance of PCSK9 in atherosclerosis progression is demonstrated by the benefits
observed in patients that have followed PCSK9-targeted therapies. The impact of these …
observed in patients that have followed PCSK9-targeted therapies. The impact of these …
Targeting LOX‐1 in atherosclerosis and vasculopathy: current knowledge and future perspectives
Abstract LOX‐1 (lectin‐like oxidized low‐density lipoprotein receptor‐1; also known as
OLR1) is the dominant receptor that recognizes and internalizes oxidized low‐density …
OLR1) is the dominant receptor that recognizes and internalizes oxidized low‐density …