Proximity extension assay proteomics and renal single cell transcriptomics uncover novel urinary biomarkers for active lupus nephritis

Y Li, C Tang, K Vanarsa, N Thai, J Castillo… - Journal of …, 2024 - Elsevier
Objective To identify urinary biomarkers that can distinguish active renal involvement in
Lupus Nephritis (LN), a severe manifestation of systemic lupus erythematosus (SLE) …

Alterations in exhausted and classical memory B cells in lupus nephritis–Relationship with disease relapse

L Zhu, YH Wong, SSH Wong, SCY Cheung… - Clinical …, 2024 - Elsevier
Introduction B cell exhaustion is a functional abnormality of B lymphocytes observed in
chronic infections and shows association with autoreactivity. The role of exhausted and …

[HTML][HTML] Transcriptome Analysis of BAFF/BAFF-R System in Murine Nephrotoxic Serum Nephritis

T Möckel, S Boegel, A Schwarting - International Journal of Molecular …, 2024 - mdpi.com
Chronic kidney disease (CKD) is an emerging cause for morbidity and mortality worldwide.
Acute kidney injury (AKI) can transition to CKD and finally to end-stage renal disease …

Expression of B-cell activating factor (BAFF) in proliferative lupus nephritis, revisited

A Beltagy, RSZ Taleb, M Allam… - Alexandria Journal of …, 2024 - Taylor & Francis
ABSTRACT Introduction Systemic Lupus Erythematosus, an autoimmune disease, can
target various organs of the human body. Lupus nephritis (LN) is a major complication …