The role of virgin olive oil components in the modulation of endothelial function

JS Perona, R Cabello-Moruno… - The Journal of nutritional …, 2006 - Elsevier
The endothelium is involved in many of the processes related to the development of
atherosclerosis, which is considered an inflammatory disease. Actually, traditional risk …

[HTML][HTML] Ketone bodies as metabolites and signalling molecules at the crossroad between inflammation and epigenetic control of cardiometabolic disorders

N Bendridi, A Selmi, A Balcerczyk, L Pirola - International journal of …, 2022 - mdpi.com
For many years, it has been clear that a Western diet rich in saturated fats and sugars
promotes an inflammatory environment predisposing a person to chronic cardiometabolic …

Palmitoleic acid has stronger anti‐inflammatory potential in human endothelial cells compared to oleic and palmitic acids

CO de Souza, CA Valenzuela, EJ Baker… - Molecular nutrition & …, 2018 - Wiley Online Library
Scope Fatty acids (FAs) may affect endothelial cell (EC) function, influencing atherogenesis
and inflammatory processes. Palmitoleic acid (POA) has been described as an anti …

Free fatty acids are independently associated with all-cause and cardiovascular mortality in subjects with coronary artery disease

S Pilz, H Scharnagl, B Tiran, U Seelhorst… - The Journal of …, 2006 - academic.oup.com
Abstract Context: Free fatty acids (FFAs) are associated with several cardiovascular risk
factors and exert harmful effects on the myocardium. Objective: The aim of our study was to …

Lipoprotein lipase: from gene to atherosclerosis

Y Li, PP He, DW Zhang, XL Zheng, FS Cayabyab… - Atherosclerosis, 2014 - Elsevier
Lipoprotein lipase (LPL) is a key enzyme in lipid metabolism and responsible for catalyzing
lipolysis of triglycerides in lipoproteins. LPL is produced mainly in adipose tissue, skeletal …

Saturated, but not unsaturated, fatty acids induce apoptosis of human coronary artery endothelial cells via nuclear factor-κB activation

K Staiger, H Staiger, C Weigert, C Haas… - Diabetes, 2006 - Am Diabetes Assoc
High nonesterified fatty acid (NEFA) concentrations, as observed in the metabolic syndrome,
trigger apoptosis of human umbilical vein endothelial cells. Since endothelial apoptosis may …

Free fatty acids as a cardiovascular risk factor

S Pilz, W März - Clinical chemistry and laboratory medicine, 2008 - degruyter.com
Free fatty acids (FFAs) serve as physiologically important energy substrates and their
release from the adipose tissue by lipolysis is regulated according to the energy demands of …

Elevated plasma free fatty acids predict sudden cardiac death: a 6.85-year follow-up of 3315 patients after coronary angiography

S Pilz, H Scharnagl, B Tiran, B Wellnitz… - European heart …, 2007 - academic.oup.com
Aims Sudden cardiac death (SCD) is the most common fatal cardiovascular event. Free fatty
acids (FFAs) exert several harmful effects on the myocardium and may therefore contribute …

Insulin sensitivity and carotid intima-media thickness: relationship between insulin sensitivity and cardiovascular risk study

M Kozakova, A Natali, J Dekker… - … , and vascular biology, 2013 - Am Heart Assoc
Objective—Despite a wealth of experimental data in animal models, the independent
association of insulin resistance with early carotid atherosclerosis in man has not been …

Elevated concentrations of nonesterified fatty acids increase monocyte expression of CD11b and adhesion to endothelial cells

WY Zhang, E Schwartz, Y Wang, J Attrep… - … , and vascular biology, 2006 - Am Heart Assoc
Objective—Monocyte proinflammatory activity has been demonstrated in obesity, insulin
resistance, and type 2 diabetes, metabolic conditions that are frequently associated with …