The immune response in multiple sclerosis

S Rodríguez Murúa, MF Farez… - Annual Review of …, 2022 - annualreviews.org
Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, and neurodegenerative
disease that affects the central nervous system (CNS). MS is characterized by immune …

Comorbid depression in medical diseases

SM Gold, O Köhler-Forsberg, R Moss-Morris… - Nature Reviews …, 2020 - nature.com
Depression is one of the most common comorbidities of many chronic medical diseases
including cancer and cardiovascular, metabolic, inflammatory and neurological disorders …

Therapeutic potential of cannabis, cannabidiol, and cannabinoid-based pharmaceuticals

CA Legare, WM Raup-Konsavage, KE Vrana - Pharmacology, 2022 - karger.com
Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …

Myelin in the central nervous system: structure, function, and pathology

C Stadelmann, S Timmler… - Physiological …, 2019 - journals.physiology.org
Oligodendrocytes generate multiple layers of myelin membrane around axons of the central
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …

Risk and protective factors for mental disorders beyond genetics: an evidence‐based atlas

C Arango, E Dragioti, M Solmi, S Cortese… - World …, 2021 - Wiley Online Library
Decades of research have revealed numerous risk factors for mental disorders beyond
genetics, but their consistency and magnitude remain uncertain. We conducted a “meta …

[HTML][HTML] Global, regional, and national burden of multiple sclerosis 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

MT Wallin, WJ Culpepper, E Nichols, ZA Bhutta… - The Lancet …, 2019 - thelancet.com
Background Multiple sclerosis is the most common inflammatory neurological disease in
young adults. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) …

Multiple sclerosis: clinical aspects

J Oh, A Vidal-Jordana, X Montalban - Current opinion in …, 2018 - journals.lww.com
A number of recent advances have been made in the clinical diagnosis and prognostication
of multiple sclerosis patients. Future research will enable the development of more accurate …

[HTML][HTML] Risk factors for type 2 diabetes mellitus: an exposure-wide umbrella review of meta-analyses

V Bellou, L Belbasis, I Tzoulaki, E Evangelou - PloS one, 2018 - journals.plos.org
Background Type 2 diabetes mellitus (T2DM) is a global epidemic associated with
increased health expenditure, and low quality of life. Many non-genetic risk factors have …

Environmental risk factors for inflammatory bowel diseases: an umbrella review of meta-analyses

D Piovani, S Danese, L Peyrin-Biroulet… - Gastroenterology, 2019 - Elsevier
Background & Aims Multiple environmental factors have been associated with the
development of inflammatory bowel diseases (IBDs). We performed an umbrella review of …

Inflammation in CNS neurodegenerative diseases

J Stephenson, E Nutma, P van der Valk, S Amor - Immunology, 2018 - Wiley Online Library
Neurodegenerative diseases, the leading cause of morbidity and disability, are gaining
increased attention as they impose a considerable socioeconomic impact, due in part to the …