Ketamine is a phencyclidine derivative, which functions primarily as an antagonist of the N-
methyl-d-aspartate receptor. It has no affinity for gamma-aminobutyric acid receptors in the …

The potential for commonly used anesthetics and sedatives to cause neuroapoptosis and
other neurodegenerative changes in the developing mammalian brain has become evident …

Background Neonates and infants requiring anaesthesia are at risk of physiological
instability and complications, but triggers for peri-anaesthetic interventions and associations …

Anesthesia and Developing Brains — Implications of the FDA Warning | New England Journal of
Medicine Skip to main content Access provided byUT MD ANDERSON CANCER CENTER The …

The burden of pain in newborn infants has been investigated in numerous studies, but little
is known about the appropriateness of the use of pain scales according to the specific type …

Importance The results of preclinical studies suggest that anesthetic drugs administered to
neonatal animals cause widespread neuronal apoptosis and later neurocognitive …

Laboratory Animal Anaesthesia, Fourth Edition provides a basic guide to anaesthesia for a
very diverse audience needing content, with straight-forward, structured style of writing …

A major limitation to structural and functional MRI (fMRI) scans is their susceptibility to head
motion artifacts. Even submillimeter movements can systematically distort functional …

Objectives: Delirium is prevalent among critically ill children, yet associated outcomes and
modifiable risk factors are not well defined. The objective of this study was to determine …

Background Adverse neurodevelopmental outcomes are observed in up to 50% of infants
after complex cardiac surgery. We sought to determine the association of perioperative …