[HTML][HTML] Drug-induced oxidative stress in cancer treatments: Angel or devil?

H Jiang, J Zuo, B Li, R Chen, K Luo, X Xiang, S Lu… - Redox Biology, 2023 - Elsevier
Oxidative stress (OS), defined as redox imbalance in favor of oxidant burden, is one of the
most significant biological events in cancer progression. Cancer cells generally represent a …

Chemotherapy: a double-edged sword in cancer treatment

N Behranvand, F Nasri, R Zolfaghari Emameh… - Cancer immunology …, 2022 - Springer
Chemotherapy is a well-known and effective treatment for different cancers; unfortunately, it
has not been as efficient in the eradication of all cancer cells as been expected. The …

Protection against chemotherapy-and radiotherapy-induced side effects: A review based on the mechanisms and therapeutic opportunities of phytochemicals

YQ Liu, XL Wang, DH He, YX Cheng - Phytomedicine, 2021 - Elsevier
Background Although great achievements have been made in the field of cancer therapy,
chemotherapy and radiotherapy remain the mainstay cancer therapeutic modalities …

Rutin: A review on extraction, identification and purification methods, biological activities and approaches to enhance its bioavailability

B Gullon, TA Lú-Chau, MT Moreira, JM Lema… - Trends in food science & …, 2017 - Elsevier
Background Rutin is a common dietary flavonoid which has received great attention in
literature, due to their pharmacological properties, including antimicrobial, anti-inflammatory …

Molecular mechanisms of anticancer effect of rutin

A Imani, N Maleki, S Bohlouli… - Phytotherapy …, 2021 - Wiley Online Library
Because of the extensive biological functions of natural substances such as bioflavonoids,
and their high safety and low costs, they could have high priority application in the health …

Molecular mechanism involved in cyclophosphamide-induced cardiotoxicity: Old drug with a new vision

A Iqubal, MK Iqubal, S Sharma, MA Ansari, AK Najmi… - Life sciences, 2019 - Elsevier
Cyclophosphamide (CP) is an important anticancer drug which belongs to the class of
alkylating agent. Cyclophosphamide is mostly used in bone marrow transplantation …

Curcumin as an anti‐inflammatory agent: Implications to radiotherapy and chemotherapy

B Farhood, K Mortezaee, NH Goradel… - Journal of cellular …, 2019 - Wiley Online Library
Cancer is the second cause of death worldwide. Chemotherapy and radiotherapy are the
most common modalities for the treatment of cancer. Experimental studies have shown that …

Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature

N Muvhulawa, PV Dludla, K Ziqubu… - Pharmacological …, 2022 - Elsevier
Chronic inflammation remains an essential complication in the pathogenesis and
aggravation of metabolic diseases. There is a growing interest in the use of medicinal plants …

[HTML][HTML] Obtaining green extracts rich in phenolic compounds from underexploited food by-products using natural deep eutectic solvents. Opportunities and …

A Palos-Hernández, MYG Fernández… - … chemistry and pharmacy, 2022 - Elsevier
Phenolic compounds have attracted scientific interest due to their bioactive properties.
Moreover, the environmental awareness has increased considerably and, with it, research …

The anticancer potential of the dietary polyphenol rutin: Current status, challenges, and perspectives

AK Farha, RY Gan, HB Li, DT Wu… - Critical Reviews in …, 2022 - Taylor & Francis
Rutin is one of the most common dietary polyphenols found in vegetables, fruits, and other
plants. It is metabolized by the mammalian gut microbiota and absorbed from the intestines …