[HTML][HTML] APOE in the bullseye of neurodegenerative diseases: Impact of the APOE genotype in Alzheimer's disease pathology and brain diseases
R Fernández-Calle, SC Konings… - Molecular …, 2022 - Springer
ApoE is the major lipid and cholesterol carrier in the CNS. There are three major human
polymorphisms, apoE2, apoE3, and apoE4, and the genetic expression of APOE4 is one of …
polymorphisms, apoE2, apoE3, and apoE4, and the genetic expression of APOE4 is one of …
Environmental and nutritional “stressors” and oligodendrocyte dysfunction: role of mitochondrial and endoplasmatic reticulum impairment
J Maiuolo, M Gliozzi, V Musolino, C Carresi, S Nucera… - Biomedicines, 2020 - mdpi.com
Oligodendrocytes are myelinating cells of the central nervous system which are generated
by progenitor oligodendrocytes as a result of maturation processes. The main function of …
by progenitor oligodendrocytes as a result of maturation processes. The main function of …
Addictive drugs modify neurogenesis, synaptogenesis and synaptic plasticity to impair memory formation through neurotransmitter imbalances and signaling …
Drug abuse changes neurophysiological functions at multiple cellular and molecular levels
in the addicted brain. Well-supported scientific evidence suggests that drugs negatively …
in the addicted brain. Well-supported scientific evidence suggests that drugs negatively …
The effects of acute oral naltrexone pretreatment on the abuse potential of intranasal methamphetamine, and the relationship between reward/punishment sensitivity …
One potential medication for treating methamphetamine use disorder is the opioid
antagonist naltrexone (NLTX). Despite encouraging preclinical findings, the results of …
antagonist naltrexone (NLTX). Despite encouraging preclinical findings, the results of …
[HTML][HTML] Microglia NLRP3 Inflammasome and Neuroimmune Signaling in Substance Use Disorders
ML Guo, SK Roodsari, Y Cheng, RE Dempsey, W Hu - Biomolecules, 2023 - mdpi.com
During the last decade, substance use disorders (SUDs) have been increasingly recognized
as neuroinflammation-related brain diseases. Various types of abused drugs (cocaine …
as neuroinflammation-related brain diseases. Various types of abused drugs (cocaine …
[HTML][HTML] Prenatal and postnatal drug exposure: focus on persistent central effects
G Costa, AE Pollack - Neural Regeneration Research, 2023 - ncbi.nlm.nih.gov
Clinical studies indicate significant use of prescription, nonprescription and
social/recreational drugs by women during pregnancy; however, limited knowledge exists …
social/recreational drugs by women during pregnancy; however, limited knowledge exists …
产前和产后药物暴露: 关注持续的中枢效应
G Costa, AE Pollack - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
Clinical studies indicate significant use of prescription, nonprescription and
social/recreational drugs by women during pregnancy; however, limited knowledge exists …
social/recreational drugs by women during pregnancy; however, limited knowledge exists …
Ketogenic diet: a potential adjunctive treatment for substance use disorders
D Kong, J Sun, J Yang, Y Li, K Bi, Z Zhang… - Frontiers in …, 2023 - frontiersin.org
Substance use disorders (SUD) can lead to serious health problems, and there is a great
interest in developing new treatment methods to alleviate the impact of substance abuse. In …
interest in developing new treatment methods to alleviate the impact of substance abuse. In …
[HTML][HTML] Astrocytes: the neglected stars in the central nervous system and drug addiction
W Chen, S Meng, Y Han, J Shi - Medical Review, 2022 - degruyter.com
With the advent of improved tools to examine the astrocytes, which have been believed to
play a supportive role in the central nervous system (CNS) for years, their participation in the …
play a supportive role in the central nervous system (CNS) for years, their participation in the …