Long non-coding RNAs in lung cancer: Unraveling the molecular modulators of MAPK signaling
Lung cancer (LC) continues to pose a significant global medical burden, necessitating a
comprehensive understanding of its molecular foundations to establish effective treatment …
comprehensive understanding of its molecular foundations to establish effective treatment …
[HTML][HTML] Epidermal growth factor receptor (EGFR): A rising star in the era of precision medicine of lung cancer
X Liu, P Wang, C Zhang, Z Ma - Oncotarget, 2017 - ncbi.nlm.nih.gov
Lung cancer is a leading cause of cancer mortality worldwide. In tumors, the important role
of noncoding RNA regulatory networks has been more and more reveal. EGFR has been …
of noncoding RNA regulatory networks has been more and more reveal. EGFR has been …
[HTML][HTML] β-Elemene enhances erlotinib sensitivity through induction of ferroptosis by upregulating lncRNA H19 in EGFR-mutant non-small cell lung cancer
Nearly half of all Asian non-small cell lung cancer (NSCLC) patients harbour epidermal
growth factor receptor (EGFR) mutations, and first-generation EGFR tyrosine kinase …
growth factor receptor (EGFR) mutations, and first-generation EGFR tyrosine kinase …
Long Noncoding RNA PVT1 Promotes Non–Small Cell Lung Cancer Cell Proliferation through Epigenetically Regulating LATS2 Expression
L Wan, M Sun, GJ Liu, CC Wei, EB Zhang… - Molecular cancer …, 2016 - AACR
Long noncoding RNAs (lncRNA) are a novel class of transcripts with no protein coding
capacity, but with diverse functions in cancer cell proliferation, apoptosis, and metastasis …
capacity, but with diverse functions in cancer cell proliferation, apoptosis, and metastasis …
[HTML][HTML] Long non-coding RNAs in anti-cancer drug resistance
Q Chen, C Wei, Z Wang, M Sun - Oncotarget, 2017 - ncbi.nlm.nih.gov
Chemotherapy is one of the basic treatments for cancers; however, drug resistance is mainly
responsible for the failure of clinical treatment. The mechanism of drug resistance is …
responsible for the failure of clinical treatment. The mechanism of drug resistance is …
The growth arrest-specific transcript 5 (GAS5): a pivotal tumor suppressor long noncoding RNA in human cancers
C Ma, X Shi, Q Zhu, Q Li, Y Liu, Y Yao, Y Song - Tumor Biology, 2016 - Springer
Long noncoding RNAs (lncRNAs), which refer to a group of RNAs with length more than 200
nucleotides and limited protein-coding potential, play a widespread role in regulating …
nucleotides and limited protein-coding potential, play a widespread role in regulating …
[HTML][HTML] LncRNA UCA1 in anti-cancer drug resistance
H Wang, Z Guan, K He, J Qian, J Cao, L Teng - Oncotarget, 2017 - ncbi.nlm.nih.gov
The pivotal role of the long non-coding RNA (lncRNA) urothelial carcinoma associated 1
(UCA1) in anti-cancer drug resistance has been confirmed in many cancers. Overexpression …
(UCA1) in anti-cancer drug resistance has been confirmed in many cancers. Overexpression …
[HTML][HTML] Long non-coding RNA UCA1 induces non-T790M acquired resistance to EGFR-TKIs by activating the AKT/mTOR pathway in EGFR-mutant non-small cell …
N Cheng, W Cai, S Ren, X Li, Q Wang, H Pan, M Zhao… - Oncotarget, 2015 - ncbi.nlm.nih.gov
The aim of this study was to explore the role of long non-coding RNA UCA1 (urothelial
cancer-associated 1) in acquired resistance to epidermal growth factor receptor tyrosine …
cancer-associated 1) in acquired resistance to epidermal growth factor receptor tyrosine …
LncRNA MALAT1 promotes lung cancer proliferation and gefitinib resistance by acting as a miR-200a sponge
C Feng, Y Zhao, Y Li, T Zhang, Y Ma, Y Liu - … de Bronconeumología (English …, 2019 - Elsevier
Introduction Lung cancer is a major public health problem, as the second causes of cancer
related death worldwide, with relatively low survival rates, and accessible drug resistance …
related death worldwide, with relatively low survival rates, and accessible drug resistance …
Long non-coding RNA MIAT in development and disease: a new player in an old game
C Sun, L Huang, Z Li, K Leng, Y Xu, X Jiang… - Journal of biomedical …, 2018 - Springer
Abstract Background Long non-coding RNAs (lncRNAs), which are a portion of non-protein-
coding RNAs (ncRNAs), have manifested a paramount role in the pathophysiology of human …
coding RNAs (ncRNAs), have manifested a paramount role in the pathophysiology of human …