Natural polymers-based light-induced hydrogels: Promising biomaterials for biomedical applications

H Samadian, H Maleki, Z Allahyari… - Coordination Chemistry …, 2020 - Elsevier
There has been a significant increase in demand for biomaterials over the last decades.
According to this fact, the design and development of more efficient and sophisticated …

Proteinaceous hydrogels for bioengineering advanced 3D tumor models

B Blanco‐Fernandez, VM Gaspar, E Engel… - Advanced …, 2021 - Wiley Online Library
The establishment of tumor microenvironment using biomimetic in vitro models that
recapitulate key tumor hallmarks including the tumor supporting extracellular matrix (ECM) is …

A predictive microfluidic model of human glioblastoma to assess trafficking of blood–brain barrier-penetrant nanoparticles

JP Straehla, C Hajal, HC Safford… - Proceedings of the …, 2022 - National Acad Sciences
The blood–brain barrier represents a significant challenge for the treatment of high-grade
gliomas, and our understanding of drug transport across this critical biointerface remains …

[HTML][HTML] Bioactive silk fibroin scaffold with nanoarchitecture for wound healing

Q Wang, S Zhou, L Wang, R You, S Yan… - Composites Part B …, 2021 - Elsevier
Scarless skin regeneration for full-thickness wounds remains a challenge in skin tissue
engineering. The surprising scar-free repair function of fetal skin has inspired that the ideal …

[HTML][HTML] A multifunctional nanofiber reinforced photo-crosslinking hydrogel for skin wound healing

F Yu, Y Li, B Zhao, X Xie, ELN Mohamed… - Composites Part B …, 2022 - Elsevier
Acute skin wounds often lead to tissue defects and bacterial infection, leading to the
suffering of patients. In this study, we reported a multifunctional nanofiber reinforced photo …

Rapid 3D bioprinting of glioblastoma model mimicking native biophysical heterogeneity

M Tang, SK Tiwari, K Agrawal, M Tan, J Dang, T Tam… - Small, 2021 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most lethal primary brain tumor characterized by high
cellular and molecular heterogeneity, hypervascularization, and innate drug resistance …

A three-dimensional (3D) organotypic microfluidic model for glioma stem cells–Vascular interactions

D Truong, R Fiorelli, ES Barrientos, EL Melendez… - Biomaterials, 2019 - Elsevier
Glioblastoma (GBM) is one of the deadliest forms of cancer. Despite many treatment options,
prognosis of GBM remains dismal with a 5-year survival rate of 4.7%. Even then, tumors …

Hyaluronic acid-based hydrogels to study cancer cell behaviors

K Goodarzi, SS Rao - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Hyaluronic acid (HA) is a natural polysaccharide and a key component of the extracellular
matrix (ECM) in many tissues. Therefore, HA-based biomaterials are extensively utilized to …

The scrambled story between hyaluronan and glioblastoma

MA Pibuel, D Poodts, M Díaz, SE Hajos… - Journal of Biological …, 2021 - ASBMB
Advances in cancer biology are revealing the importance of the cancer cell
microenvironment on tumorigenesis and cancer progression. Hyaluronan (HA), the main …

[HTML][HTML] In vitro biomimetic models for glioblastoma-a promising tool for drug response studies

T Stanković, T Ranđelović, M Dragoj, SS Burić… - Drug Resistance …, 2021 - Elsevier
The poor response of glioblastoma to current treatment protocols is a consequence of its
intrinsic drug resistance. Resistance to chemotherapy is primarily associated with …