Skin fibrosis, a pathological process featured by fibroblast activation and extracellular matrix
(ECM) deposition, makes a significant contribution to morbidity. Studies have identified …

In mammals, sperm-borne regulators can be transferred to oocytes during fertilization and
have different effects on the formation of pronuclei, the first cleavage of zygotes, the …

Septins (SEPTs) are filamentous guanosine-5′-triphosphate (GTP)-binding proteins, which
affect microtubule (MT)-dependent functions including membrane trafficking and cell …

The localization of NQO1 near acetylated microtubules has led to the hypothesis that NQO1
may work in concert with the NAD+-dependent deacetylase SIRT2 to regulate acetyl α …

Lysosomes are key organelles maintaining cellular homeostasis in health and disease.
Here, we report the identification of N‐deacetylase and N‐sulfotransferase 3 (NDST3) as a …

The RHO GTPase family has been suggested to play critical roles in cell growth, migration,
and polarization. Regulators and effectors of RHO GTPases have been extensively explored …

The mechanisms underlying axon regeneration in mature neurons are relevant to the
understanding of normal nervous system maintenance and for developing therapeutic …

The work of the Gulf War Illness (GWI) Consortium and that of basic and clinical researchers
across the USA have resulted in a better understanding in recent years of the pathological …

The acetylation of the lysine 40 residue of α-tubulin was described more than 30 years ago
and has been the subject of intense research ever since. Although the exact function of this …

The primary cilium is a cellular antenna found on the surface of many eukaryotic cells,
whose main role is to sense and transduce signals that regulate growth, development, and …