[HTML][HTML] Single-cell transcriptomics characterizes cell types in the subventricular zone and uncovers molecular defects impairing adult neurogenesis

V Zywitza, A Misios, L Bunatyan, TE Willnow… - Cell reports, 2018 - cell.com
Neural stem cells (NSCs) contribute to plasticity and repair of the adult brain. Niches
harboring NSCs regulate stem cell self-renewal and differentiation. We used comprehensive …

Isolation, identification, and characterization of cancer stem cells: A review

MR Abbaszadegan, V Bagheri… - Journal of cellular …, 2017 - Wiley Online Library
Cancer stem cells (CSCs) or tumor‐initiating cells (TICs) as a small subset of neoplastic
cells are able to produce a tumor (tumorigenesis), maintain the population of tumorigenic …

CD133: a stem cell biomarker and beyond

Z Li - Experimental hematology & oncology, 2013 - Springer
Cancer stem cells (CSCs) or tumor initiating cells (TICs) contribute to tumorigenesis,
metastasis, recurrence and chemoresistance. CD133, a pentaspan membrane glycoprotein …

CD133 expression is not restricted to stem cells, and both CD133+ and CD133 metastatic colon cancer cells initiate tumors

SV Shmelkov, JM Butler, AT Hooper… - The Journal of …, 2008 - Am Soc Clin Investig
Colon cancer stem cells are believed to originate from a rare population of putative CD133+
intestinal stem cells. Recent publications suggest that a small subset of colon cancer cells …

Exosomes: Revisiting their role as “garbage bags”

M Vidal - Traffic, 2019 - Wiley Online Library
In recent years, the term “extracellular vesicle”(EV) has been used to define different types of
vesicles released by various cells. It includes plasma membrane‐derived vesicles …

Lung cancer stem cell markers as therapeutic targets: an update on signaling pathways and therapies

Y Zheng, L Wang, L Yin, Z Yao, R Tong, J Xue… - Frontiers in …, 2022 - frontiersin.org
Cancer stem cells, a relatively small group of self-renewing cancer cells, were first isolated
from acute myeloid leukemia. These cells can play a crucial role in tumor metastasis …

Single-cell analysis reveals transcriptional heterogeneity of neural progenitors in human cortex

MB Johnson, PP Wang, KD Atabay, EA Murphy… - Nature …, 2015 - nature.com
The human cerebral cortex depends for its normal development and size on a precisely
controlled balance between self-renewal and differentiation of diverse neural progenitor …

CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges

P Grosse‐Gehling, CA Fargeas, C Dittfeld… - The Journal of …, 2013 - Wiley Online Library
The cancer stem cell (CSC) hypothesis, despite the limitations of the currently available
models and assays, has ushered in a new era of excitement in cancer research. The …

CD133, a novel marker for human prostatic epithelial stem cells

GD Richardson, CN Robson, SH Lang… - Journal of cell …, 2004 - journals.biologists.com
Stem cells are clonogenic cells with self-renewal and differentiation properties, which may
represent a major target for genetic damage leading to prostate cancer and benign prostatic …

Stem cell marker CD133 affects clinical outcome in glioma patients

F Zeppernick, R Ahmadi, B Campos, C Dictus… - Clinical cancer …, 2008 - AACR
Purpose: The CD133 antigen has been identified as a putative stem cell marker in normal
and malignant brain tissues. In gliomas, it is used to enrich a subpopulation of highly …