The potential use of stem cell‐based therapies for the repair and regeneration of various
tissues and organs offers a paradigm shift in plastic and reconstructive surgery. The use of …

Critical-sized bone defects, or CSDs, are defined as bone defects that cannot be
regenerated by themselves and require surgical intervention via employing specific …

Adipose-derived stem cells (ASCs) can be applied extensively in the clinic because they can
be easily isolated and cause less donor-site morbidity; however, their application can be …

Background Mesenchymal stem cells derived from adipose tissue (ADSC) are multipotent
stem cells, originated from the vascular-stromal compartment of fat tissue. ADSC are used as …

Objective—Tremendous efforts have been made to establish effective therapeutic
neovascularization using adipose tissue-derived stromal vascular fraction (SVF), but the …

Improving vascularization of tissue-engineered bone can advance cell performance in vivo
and further promote bone regeneration. How to achieve a functional vascular network within …

Slow vascularization rate is considered one of the main drawbacks of scaffolds used in
wound healing. Several efforts, including cellular and acellular technologies, have been …

Tissue regeneration is impaired in aged individuals. Adipose-derived mesenchymal stromal
cells (ADSCs), a promising source for cell therapy, were shown to secrete various …

Background: Adipose stem cells represent a heterogenous population. Understanding the
functional characteristics of subpopulations will be useful in developing adipose stem cell …

Multipotent mesenchymal stem cells (MSCs) are found in various tissues and can proliferate
extensively in vitro. MSCs have been used in preclinical animal studies and clinical trials in …