Purpose Although guidelines can reduce postoperative opioid prescription, the problem of
unused opioids persists. We assessed the pattern of opioid prescription and utilization after …

Background Opioid use is common and associated with side effects and risks.
Consequently, analgesic strategies to reduce opioid utilization have been developed …

We read with interest three recently published articles in which opioid-free anesthesia was
discussed. 1–3 However, we would like to address several concerns regarding the scientific …

Background Knee arthritis is a leading cause of limited function and long-term disability in
older adults. Despite a technically successful total knee arthroplasty (TKA), around 20% of …

Introduction Regional techniques are a key component of multimodal analgesia and help
decrease opioid use perioperatively, but some techniques may not be suitable for all …

Exposure to opioid analgesics due to surgery increases the risk of new persistent opioid
use. A mechanistic hypothesis for opioids' abuse liability rests on the belief that in addition to …

Obesity and obstructive sleep apnea are considered independent risk factors that can
adversely affect perioperative outcomes. A combination of these two conditions in the …

Background Opioid-free anesthesia (OFA) provides adequate analgesia and can reduce
postoperative opioid consumption, but its efficacy in spontaneous ventilation video-assisted …

Background: Enhanced Recovery After Surgery (ERAS) protocol for esophagectomy may
reduce the high incidence of postoperative morbidity and mortality. The aim of this study was …

Hepatocellular carcinoma (HCC) is a fatal cancer worldwide, and surgical resection remains
the standard treatment. Postoperative opioid prescription has been believed to affect cancer …