[HTML][HTML] Emerging functions of thrombospondin-1 in immunity
S Kaur, DD Roberts - Seminars in Cell & Developmental Biology, 2024 - Elsevier
Thrombospondin-1 is a secreted matricellular glycoprotein that modulates cell behavior by
interacting with components of the extracellular matrix and with several cell surface …
interacting with components of the extracellular matrix and with several cell surface …
[HTML][HTML] Molecular mechanisms of thrombospondin-2 modulates tumor vasculogenic mimicry by PI3K/AKT/mTOR signaling pathway
J Huang, C Wang, Y Hou, Y Tian, Y Li, H Zhang… - Biomedicine & …, 2023 - Elsevier
Vasculogenic mimicry (VM) differs from the classical tumor angiogenesis model. VM does
not depend on endothelial cells; instead, highly aggressive tumor cells mimic endothelial …
not depend on endothelial cells; instead, highly aggressive tumor cells mimic endothelial …
[HTML][HTML] Prognostic implication and immunological role of PSMD2 in lung adenocarcinoma
H Zhao, G Lu - Frontiers in Genetics, 2022 - frontiersin.org
Background: Although previous studies reported that 26S proteasome non-ATPase
regulatory subunit 2 (PSMD2) is involved in many human cancers. However, its clinical …
regulatory subunit 2 (PSMD2) is involved in many human cancers. However, its clinical …
Systematic analysis of integrated bioinformatics to identify upregulated THBS2 expression in colorectal cancer cells inhibiting tumour immunity through the HIF1A …
Y Liu, C Jiang, C Xu, L Gu - Cancer Cell International, 2023 - Springer
Background THBS2, a member of the extracellular matrix glycoprotein family, can effectively
inhibit tumour growth and angiogenesis. This study aimed to investigate the biological role …
inhibit tumour growth and angiogenesis. This study aimed to investigate the biological role …
[HTML][HTML] Targeting thrombospondin-2 retards liver fibrosis by inhibiting TLR4-FAK/TGF-β signaling
N Zhang, X Wu, W Zhang, Y Sun, X Yan, A Xu, Q Han… - JHEP Reports, 2024 - Elsevier
Background & Aims Thrombospondin-2 (THBS2) expression is associated with liver fibrosis
regardless of etiology. However, the role of THBS2 in the pathogenesis of liver fibrosis has …
regardless of etiology. However, the role of THBS2 in the pathogenesis of liver fibrosis has …
LncRNA AGAP2 antisense RNA 1 stabilized by insulin-like growth factor 2 mRNA binding protein 3 promotes macrophage M2 polarization in clear cell renal cell …
P Xu, D Feng, J Wang, YD Wang, G Xie, B Zhang… - Cancer Cell …, 2023 - Springer
Background Increasing evidence highlights the potential role of long non-coding RNAs
(lncRNAs) in the biological behaviors of renal cell carcinoma (RCC). Here, we explored the …
(lncRNAs) in the biological behaviors of renal cell carcinoma (RCC). Here, we explored the …
Comparative transcriptomic analysis and mechanistic characterization revealed the use of formononetin for bladder cancer treatment
H Zhou, P Wang, X Qin, X Zhang, KP Lai, J Chen - Food & Function, 2023 - pubs.rsc.org
Bladder cancer is one of the most common cancers worldwide, with 213 000 deaths
reported in 2020. Patients with a progression from non-muscle-invasive bladder cancer to …
reported in 2020. Patients with a progression from non-muscle-invasive bladder cancer to …
Identification of Key Genes Associated with Tumor Microenvironment Infiltration and Survival in Gastric Adenocarcinoma via Bioinformatics Analysis
G Konstantis, G Tsaousi, C Pourzitaki… - Cancers, 2024 - mdpi.com
Simple Summary This study aimed to pinpoint immune-related genes that show heightened
activity in cancerous tissue and explore their correlation with cell infiltration in the tumor …
activity in cancerous tissue and explore their correlation with cell infiltration in the tumor …
Transcription Analysis of the THBS2 Gene through Regulation by Potential Noncoding Diagnostic Biomarkers and Oncogenes of Gastric Cancer in the ECM …
A Barani, K Beikverdi, B Mashhadi… - … Journal of Genomics, 2023 - Wiley Online Library
Background. Gastric cancer (GC) is the second most frequent cause of cancer‐related death
worldwide and the fourth most common malignancy. Despite significant improvements in …
worldwide and the fourth most common malignancy. Despite significant improvements in …
[HTML][HTML] Single-cell RNA combined with bulk RNA analysis to explore oxidative stress and energy metabolism factors and found a new prostate cancer oncogene …
M Miao, Y Song, M Jin, Y Du, P Xin, Y Jiang… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Background: Prostate cancer is the most common malignancy among men worldwide, and
its diagnosis and treatment are challenging due to its heterogeneity. Methods: Integrating …
its diagnosis and treatment are challenging due to its heterogeneity. Methods: Integrating …