Background Many studies have recently reported the association of concomitant
medications with the response and survival in patients with non-small-cell lung cancer …

The importance of statins in cancer has been discussed in many studies. They are known for
their anticancer properties against solid tumors of the liver or lung, as well as diffuse …

Background Osteosarcoma (OS) is the most prevalent primary bone malignancy affecting
adolescents, yet the emergence of chemoradiotherapeutic resistance has limited efforts to …

Atorvastatin (ATV) has attracted considerable attention as a potential therapeutic agent for
cancer because it inhibits cancer cell proliferation by suppressing the mevalonate pathway …

Simple Summary Ovarian cancer (OC) is known for its poor prognosis, due to the absence of
reliable biomarkers and its late diagnosis, since the early-stage disease is almost …

Polyalthia belong to the Annonaceae family and are a type of evergreen tree distributed
across many tropical and subtropical regions. Polyalthia species have been used long term …

There is an unmet clinical need to develop novel strategies to overcome resistance to
tyrosine kinase inhibitors (TKI) in patients with oncogene-driven lung adenocarcinoma …

Genetic manipulations and pharmaceutical interventions to disturb lipid metabolism
homeostasis have emerged as an attractive approach for the management of cancer …

The metabolic and signaling pathways regulating aggressive mesenchymal colorectal
cancer (CRC) initiation and progression through the serrated route are largely unknown …

The constitutive and dysregulated expression of the transcription factor MYCN has a central
role in the pathogenesis of the paediatric brain tumour medulloblastoma, with an increased …