The failure of animal models to predict therapeutic responses in humans is a major problem
that also brings into question their use for basic research. Organ-on-a-chip (organ chip) …

Biomedical research is undergoing a paradigm shift towards approaches centred on human
disease models owing to the notoriously high failure rates of the current drug development …

Acute exposure to high-dose gamma radiation due to radiological disasters or cancer
radiotherapy can result in radiation-induced lung injury (RILI), characterized by acute …

Organ-on-a-chip (OOAC) is an emerging technology based on microfluid platforms and in
vitro cell culture that has a promising future in the healthcare industry. The numerous …

In some patients, COVID-19 can trigger neurological symptoms with unclear pathogenesis.
Here we describe a microphysiological system integrating alveolus and blood–brain barrier …

Drug evaluation has always been an important area of research in the pharmaceutical
industry. However, animal welfare protection and other shortcomings of traditional drug …

Atmospheric pollutants, including particulate matters, nanoparticles, bioaerosols, and some
chemicals, have posed serious threats to the environment and the human's health. The …

As post‐COVID complications, chronic respiratory diseases are one of the foremost causes
of mortality. The quest for a cure for this recent global challenge underlines that the lack of …

The intertwined relationship between structure and function has been key to understanding
human organ physiology and disease pathogenesis. An organ-on-a-chip (organ chip) is a …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing the coronavirus
disease 2019 (COVID-19), has provoked more than six million deaths worldwide and …