Saponins, classification and occurrence in the plant kingdom

JP Vincken, L Heng, A de Groot, H Gruppen - Phytochemistry, 2007 - Elsevier
Saponins are a structurally diverse class of compounds occurring in many plant species,
which are characterized by a skeleton derived of the 30-carbon precursor oxidosqualene to …

Anti-viral triterpenes: a review

P Darshani, S Sen Sarma, AK Srivastava… - Phytochemistry …, 2022 - Springer
Triterpenes are naturally occurring derivatives biosynthesized following the isoprene rule of
Ruzicka. The triterpenes have been reported to possess a wide range of therapeutic …

On the origins of triterpenoid skeletal diversity

R Xu, GC Fazio, SPT Matsuda - Phytochemistry, 2004 - Elsevier
The triterpenoids are a large group of natural products derived from C30 precursors. Nearly
200 different triterpene skeletons are known from natural sources or enzymatic reactions that …

Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)

AM Brinker, J Ma, PE Lipsky, I Raskin - Phytochemistry, 2007 - Elsevier
Plants in the genus Tripterygium, such as Tripterygium wilfordii Hook. f., have a long history
of use in traditional Chinese medicine. In recent years there has been considerable interest …

Biosynthesis, total synthesis, structural modifications, bioactivity, and mechanism of action of the quinonemethide triterpenoid celastrol

Y Lu, Y Liu, J Zhou, D Li, W Gao - Medicinal research reviews, 2021 - Wiley Online Library
Celastrol, a quinonemethide triterpenoid, was extracted from Tripterygium wilfordii Hook. F.
in 1936 for the first time. Almost 70 years later, it is considered one of the molecules most …

Friedelanetype triterpene cyclase in celastrol biosynthesis from Tripterygium wilfordii and its application for triterpenes biosynthesis in yeast

J Zhou, T Hu, L Gao, P Su, Y Zhang, Y Zhao… - New …, 2019 - Wiley Online Library
Celastrol is a promising bioactive compound isolated from Tripterygium wilfordii and has
been shown to possess many encouraging preclinical applications. However, the celastrol …

The effect of methyl jasmonate on triterpene and sterol metabolisms of Centella asiatica, Ruscus aculeatus and Galphimia glauca cultured plants

S Mangas, M Bonfill, L Osuna, E Moyano, J Tortoriello… - Phytochemistry, 2006 - Elsevier
Considering that exogenously applied methyl jasmonate can enhance secondary metabolite
production in a variety of plant species and that 2, 3-oxidosqualene is a common precursor …

Screening of 2A peptides for polycistronic gene expression in yeast

TM Souza-Moreira, C Navarrete, X Chen… - FEMS Yeast …, 2018 - academic.oup.com
A complexity of pathway expression in yeast compared to prokaryotes is the need for
separate promoters and terminators for each gene expressed. Single transcript expression …

Antiplasmodial potential of traditional phytotherapy of some remedies used in treatment of malaria in Meru–Tharaka Nithi County of Kenya

CN Muthaura, JM Keriko, C Mutai, A Yenesew… - Journal of …, 2015 - Elsevier
Ethnopharmacological relevance Medicinal plants play a major role in many communities
across the world, in the treatment and prevention of disease and the promotion of general …

Revisão da Maytenus ilicifolia Mart. ex Reissek, Celastraceae. Contribuição ao estudo das propriedades farmacológicas

R Santos-Oliveira, S Coulaud-Cunha… - Revista Brasileira de …, 2009 - SciELO Brasil
A Maytenus ilicifolia Mart. ex Reissek, Celastraceae, vem sendo utilizada à muitos anos na
terapêutica clínica, contudo suas propriedades farmacológicas continuam sob estudo. O …