Pristimerin has been shown to be cytotoxic to several cancer cell lines. In the present work,
the cytotoxicity of pristimerin was evaluated in human tumor cell lines and in human …

A Maytenus ilicifolia Mart. ex Reissek, Celastraceae, vem sendo utilizada à muitos anos na
terapêutica clínica, contudo suas propriedades farmacológicas continuam sob estudo. O …

Covering: up through 2002This review highlights mutagenesis studies of terpene synthases,
specifically sesquiterpene synthases and oxidosqualene cyclases. Mutagenesis studies of …

Ethnopharmacological relevance The leaves, stems and roots of Alchornea cordifolia
(Schumach. and Thonn.) Müll. Arg. are used as traditional medicine in many African …

The use of natural products has definitely been the most successful strategy in the discovery
of novel medicines. Secondary metabolites from terrestrial and marine organisms have …

The present study describes the leishmanicidal and trypanocidal activities of two
quinonemethide triterpenes, maytenin (1) and pristimerin (2), isolated from Maytenus …

The Celastraceae family comprises about 96 genera and more than 1.350 species,
occurring mainly in tropical and subtropical regions of the world. The species of this family …

Among the biologically active triterpenes, friedelin has the most-rearranged structure
produced by the oxidosqualene cyclases and is the only one containing a cetonic group. In …

Abstract The native Brazilian plant Maytenus ilicifolia accumulates a set of quinone methide
triterpenoids with important pharmacological properties, of which maytenin, pristimerin and …

This work describes the isolation of the secondary metabolites identified as the
quinonemethides maytenin (1) and pristimerin (2) from Maytenus ilicifolia extracts obtained …