Outcome prognostication in traumatic brain injury (TBI) is important but challenging due to
heterogeneity of the disease. The aim of this systematic review is to present the current state …

Background Traumatic injuries are physical insults to the body that are prevalent worldwide.
Many individuals involved in accidents suffer injuries affecting a number of extremities and …

Importance Traumatic brain injury (TBI) leads to 2.9 million visits to US emergency
departments annually and frequently involves a disorder of consciousness (DOC). Early …

Complex metabolic disruption is a crucial aspect of the pathophysiology of traumatic brain
injury (TBI). Associations between this and systemic metabolism and their potential …

BACKGROUND: Early computerized tomography (CT) abnormalities are important
predictors of outcome after traumatic brain injury (TBI). OBJECTIVE: To develop a novel CT …

Research in traumatic brain injury (TBI) is challenging for several reasons; in particular, the
heterogeneity between patients regarding causes, pathophysiology, treatment, and …

Systemic inflammation impacts outcome after traumatic brain injury (TBI), but most TBI
biomarker studies have focused on brain-specific proteins. C-reactive protein (CRP) is a …

Background Traumatic brain injury refers to a broad range of neurological, cognitive, and
emotional factors that result from the application of an external force to the head. Individuals …

Cerebral autoregulation, as measured using the pressure reactivity index (PRx), has been
related to global patient outcome in adult patients with traumatic brain injury (TBI). To date …

Background Monitoring cerebrovascular reactivity in adult traumatic brain injury (TBI) has
been linked to global patient outcome. Three intra-cranial pressure (ICP)-derived indices …