Present in the genomes of bacteria and eukaryotic organelles, group II introns are an
ancient class of ribozymes and retroelements that are believed to have been the ancestors …

Long non-coding RNAs (lncRNAs) are recently-discovered transcripts that regulate vital
cellular processes and are crucially connected to diseases. Despite their unprecedented …

The ubiquitous presence of long noncoding RNAs (lncRNAs) in eukaryotes points to the
importance of understanding how their sequences impact function. As many lncRNAs …

Group II introns are remarkable mobile retroelements that use the combined activities of an
autocatalytic RNA and an intron‐encoded reverse transcriptase (RT) to propagate efficiently …

Group II introns are self-splicing ribozymes that share a reaction mechanism and a common
ancestor with the eukaryotic spliceosome, thereby providing a model system for …

Bacterial group II introns are large catalytic RNAs related to nuclear spliceosomal introns
and eukaryotic retrotransposons. They self-splice, yielding mature RNA, and integrate into …

Compact RNA structural motifs control many aspects of gene expression, but we lack
methods for finding these structures in the vast expanse of multi-kilobase RNAs. To adopt …

Novel, profound and unexpected roles of long non-coding RNAs (lncRNAs) are emerging in
critical aspects of gene regulation. Thousands of lncRNAs have been recently discovered in …

Introns are ubiquitous in eukaryotic genomes and have long been considered as 'junk
RNA'but the huge energy expenditure in their transcription, removal, and degradation …

Group II introns are ribozymes that catalyze their self-excision and function as retroelements
that invade DNA. As retrotransposons, group II introns form ribonucleoprotein (RNP) …