The generation of islet-like endocrine clusters from human pluripotent stem cells (hPSCs)
has the potential to provide an unlimited source of insulin-producing β cells for the treatment …

Advances in biomaterial science have allowed for unprecedented insight into the ability of
material cues to influence stem cell function. These material approaches better recapitulate …

Peripheral nerves participate in bone growth and repair by secreting neurotransmitters, and
enable new bone to possess physiological bone-sensing capability. However, it is difficult to …

Noncovalent interactions between cells and environmental cues have been recognized as
fundamental physiological interactions that regulate cell behavior. However, the effects of …

Abstract 3D bioprinting holds great promise toward fabricating biomimetic living constructs in
a bottom-up assembly manner. To date, various emergences of living constructs have been …

Spinal cord injury (SCI) often causes loss of sensory and motor function resulting in a
significant reduction in quality of life for patients. Currently, no therapies are available that …

Spinal cord injuries (SCIs) can lead to significant neurological deficits and lifelong disability,
with far-reaching physical, psychological, and economic consequences for affected …

Tissue engineering aims to generate functional biological substitutes to repair, sustain,
improve, or replace tissue function affected by disease. With the rapid development of space …

Anticancer therapies and regenerative medicine are being developed to destroy tumor cells,
as well as remodel, replace, and support injured organs and tissues. Nowadays, a suitable …

Dental pulp is the only soft tissue in the tooth which plays a crucial role in maintaining
intrinsic multi-functional behaviors of the dentin-pulp complex. Nevertheless, the restoration …