[HTML][HTML] Targeting integrin pathways: mechanisms and advances in therapy

X Pang, X He, Z Qiu, H Zhang, R Xie, Z Liu… - … and Targeted Therapy, 2023 - nature.com
Integrins are considered the main cell-adhesion transmembrane receptors that play
multifaceted roles as extracellular matrix (ECM)-cytoskeletal linkers and transducers in …

[HTML][HTML] Matrix metalloproteinases shape the tumor microenvironment in cancer progression

S Niland, AX Riscanevo, JA Eble - International journal of molecular …, 2021 - mdpi.com
Cancer progression with uncontrolled tumor growth, local invasion, and metastasis depends
largely on the proteolytic activity of numerous matrix metalloproteinases (MMPs), which …

[HTML][HTML] SRC kinase-mediated signaling pathways and targeted therapies in breast cancer

J Luo, H Zou, Y Guo, T Tong, L Ye, C Zhu, L Deng… - Breast Cancer …, 2022 - Springer
Breast cancer (BC) has been ranked the most common malignant tumor throughout the
world and is also a leading cause of cancer-related deaths among women. SRC family …

Impact of imidacloprid exposure on the biochemical responses, transcriptome, gut microbiota and growth performance of the Pacific white shrimp Litopenaeus …

Z Fu, F Han, K Huang, J Zhang, JG Qin, L Chen… - Journal of Hazardous …, 2022 - Elsevier
The widespread use of neonicotinoid insecticides, such as imidacloprid, in agriculture is one
of the key factors for the drop in the survival of invertebrates, including decapod crustaceans …

A review on the recent progress, opportunities, and challenges of 4D printing and bioprinting in regenerative medicine

P Pourmasoumi, A Moghaddam… - Journal of …, 2023 - Taylor & Francis
Abstract Four-dimensional (4 D) printing is a novel emerging technology, which can be
defined as the ability of 3 D printed materials to change their form and functions. The term …

[HTML][HTML] Roles of focal adhesion proteins in skeleton and diseases

S Chen, T He, Y Zhong, M Chen, Q Yao, D Chen… - … Pharmaceutica Sinica B, 2023 - Elsevier
The skeletal system, which contains bones, joints, tendons, ligaments and other elements,
plays a wide variety of roles in body shaping, support and movement, protection of internal …

Talin in mechanotransduction and mechanomemory at a glance

BT Goult, NH Brown, MA Schwartz - Journal of cell science, 2021 - journals.biologists.com
Talins are cytoskeletal linker proteins that consist of an N-terminal head domain, a flexible
neck region and a C-terminal rod domain made of 13 helical bundles. The head domain …

Upregulated cytoskeletal proteins promote pathological angiogenesis in moyamoya disease

S He, J Zhang, Z Liu, Y Wang, X Hao, X Wang, Z Zhou… - Stroke, 2023 - Am Heart Assoc
BACKGROUND: Moyamoya disease (MMD) is a rare progressive vascular disease that
leads to intracranial internal carotid artery stenosis and eventual occlusion. However, its …

[HTML][HTML] Substrate stiffness modulates the viscoelastic properties of MCF-7 cells

JC Gil-Redondo, A Weber, B Zbiral… - Journal of the …, 2022 - Elsevier
Cells sense stiffness of surrounding tissues and adapt their activity, proliferation, motility and
mechanical properties based on such interactions. Cells probe the stiffness of the substrate …

[HTML][HTML] To stick or not to stick: The multiple roles of cell adhesion molecules in neural circuit assembly

T Moreland, FE Poulain - Frontiers in Neuroscience, 2022 - frontiersin.org
Precise wiring of neural circuits is essential for brain connectivity and function. During
development, axons respond to diverse cues present in the extracellular matrix or at the …