Glycolysis mediates neuron specific histone acetylation in valproic acid-induced human excitatory neuron differentiation
A Chen, M Wang, C Xu, Y Zhao, P Xian, Y Li… - Frontiers in Molecular …, 2023 - frontiersin.org
Pregnancy exposure of valproic acid (VPA) is widely adopted as a model of environmental
factor induced autism spectrum disorder (ASD). Increase of excitatory/inhibitory synaptic …
factor induced autism spectrum disorder (ASD). Increase of excitatory/inhibitory synaptic …
Vitamin A ameliorates valproic acid-induced autism-like symptoms in developing zebrafish larvae by attenuating oxidative stress and apoptosis
J Wang, L Zou, P Jiang, M Yao, Q Xu, Q Hong, J Zhu… - NeuroToxicology, 2024 - Elsevier
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social
deficits and repetitive/stereotyped behaviors. Prenatal exposure to valproic acid (VPA) has …
deficits and repetitive/stereotyped behaviors. Prenatal exposure to valproic acid (VPA) has …
Insights on three dimensional organoid studies for stem cell therapy in regenerative medicine
Regenerative medicine has developed as a promising discipline that utilizes stem cells to
address limitations in traditional therapies, using innovative techniques to restore and repair …
address limitations in traditional therapies, using innovative techniques to restore and repair …
Dysregulation of the chromatin environment leads to differential alternative splicing as a mechanism of disease in a human model of autism spectrum disorder
CS Leung, SJ Rosenzweig, B Yoon… - Human Molecular …, 2023 - academic.oup.com
Autism spectrum disorder (ASD) affects 1 in 44 children. Chromatin regulatory proteins are
overrepresented among genes that contain high risk variants in ASD. Disruption of the …
overrepresented among genes that contain high risk variants in ASD. Disruption of the …
Brain Chimeroids reveal individual susceptibility to neurotoxic triggers
N Antón-Bolaños, I Faravelli, T Faits, S Andreadis… - Nature, 2024 - nature.com
Interindividual genetic variation affects the susceptibility to and progression of many
diseases,. However, efforts to study how individual human brains differ in normal …
diseases,. However, efforts to study how individual human brains differ in normal …
Regulation of K+-Dependent Na+/Ca2+-Exchangers (NCKX)
M Al-Khannaq, J Lytton - International journal of molecular sciences, 2022 - mdpi.com
Potassium-dependent sodium-calcium exchangers (NCKX) have emerged as key
determinants of calcium (Ca2+) signaling and homeostasis, especially in environments …
determinants of calcium (Ca2+) signaling and homeostasis, especially in environments …
Enhancing social behavior in an autism spectrum disorder mouse model: investigating the underlying mechanisms of Lactiplantibacillus plantarum intervention
CM Chen, CC Wu, Y Kim, WY Hsu, YC Tsai… - Gut Microbes, 2024 - Taylor & Francis
Autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting over 1% of the
global population. Individuals with ASD often exhibit complex behavioral conditions …
global population. Individuals with ASD often exhibit complex behavioral conditions …
Development and Optimization of a Lactate Dehydrogenase Assay Adapted to 3D Cell Cultures
H Castiglione, L Madrange, T Lemonnier, JP Deslys… - Organoids, 2024 - mdpi.com
In recent years, 3D cell culture systems have emerged as sophisticated in vitro models,
providing valuable insights into human physiology and diseases. The transition from …
providing valuable insights into human physiology and diseases. The transition from …
The Autism Spectrum Disorder and Its Possible Origins in Pregnancy
RM Botelho, ALM Silva, AU Borbely - International Journal of …, 2024 - mdpi.com
Autism Spectrum Disorder (ASD) belongs to the group of neurodevelopmental disorders,
and has a high prevalence, affecting 1 in 100 children according to data from the World …
and has a high prevalence, affecting 1 in 100 children according to data from the World …
Mesenchymal Stem Cells and Purinergic Signaling in Autism Spectrum Disorder: Bridging the Gap between Cell-Based Strategies and Neuro-Immune Modulation
A Wikarska, K Roszak, K Roszek - Biomedicines, 2024 - mdpi.com
The prevalence of autism spectrum disorder (ASD) is still increasing, which means that this
neurodevelopmental lifelong pathology requires special scientific attention and efforts …
neurodevelopmental lifelong pathology requires special scientific attention and efforts …