Although great efforts have been made to elucidate the pathological mechanisms of renal
diseases and potential prevention and treatment targets that would allow us to retard kidney …

Epitranscriptomics, ie, chemical modifications of RNA molecules, has proven to be a new
layer of modulation and regulation of protein expression, asking for the revisiting of some …

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection and is characterized by multiple biological and clinical features. N 6 …

The N6-methyladenosine modification is one of the most abundant post-transcriptional
modifications in ribonucleic acid (RNA) molecules. Using molecular dynamics simulations …

Adenosine to inosine (A-to-I) RNA editing is one of the most frequent RNA modifications
found in the mammalian transcriptome. Recent studies clearly indicate that RNA editing …

Transfer RNAs (tRNAs) are the most highly modified cellular RNAs, both with respect to the
proportion of nucleotides that are modified within the tRNA sequence and with respect to the …

RNA modifications are mostly dynamically reversible post-transcriptional modifications, of
which m6A is the most prevalent in eukaryotic mRNAs. A growing number of studies indicate …

Background RNA methylation modifications, such as N1-methyladenosine/N6-
methyladenosine/N5-methylcytosine (m1A/m6A/m5C), are the most common RNA …

RNA modifications modulate essential cellular functions. However, it is challenging to
quantitatively identify the differences in RNA modifications. To further improve the single …

Many studies have shown RNA modifications including deamination of cytosine to uracil (C-
to-U), deamination of adenosine to inosine (A-to-I), N1-methyladenosine (m1A), 5 …