Classic psychedelics, such as LSD, psilocybin, and the DMT-containing beverage
ayahuasca, show some potential to treat depression, anxiety, and addiction. Importantly …

Mental disorders represent common brain diseases characterized by substantial
impairments of social and cognitive functions. The neurobiological causes and mechanisms …

Abstract N, N-dimethyltryptamine (DMT) is a component of the ayahuasca brew traditionally
used for ritual and therapeutic purposes across several South American countries. Here, we …

Depression and cognitive disorders are diseases with complex and not-fully understood
etiology. Unfortunately, the COVID-19 pandemic dramatically increased the prevalence of …

Depression is the most common type of neuropsychiatric illness and has increasingly
become a major cause of disability. Unfortunately, the recent global pandemic of COVID-19 …

CaMKII and CaMKIV are calcium/calmodulin-dependent kinases playing a rudimentary role
in many regulatory processes in the organism. These kinases attract increasing interest due …

Objective: The incidence rate of major depression in adolescents reaches approximately
14%. This disorder is usually recurrent, without remission of symptoms even after …

Emotional stress is a form of stress evoked by processing negative mental experience rather
than an organic or physical disturbance and is a frequent cause of neuropsychiatric …

This review analyzes the current scientific literature on the role of the Sigma1R chaperone in
the pathogenesis of depressive disorders and pharmacodynamics of antidepressants. As a …

Though a great many of studies on the development of antidepressants for the therapy of
major depression disorder (MDD) and the development of antidepressants have been …