[HTML][HTML] Towards an understanding of psychedelic-induced neuroplasticity
AE Calder, G Hasler - Neuropsychopharmacology, 2023 - nature.com
Classic psychedelics, such as LSD, psilocybin, and the DMT-containing beverage
ayahuasca, show some potential to treat depression, anxiety, and addiction. Importantly …
ayahuasca, show some potential to treat depression, anxiety, and addiction. Importantly …
[HTML][HTML] Protein misfolding and aggregation in the brain: common pathogenetic pathways in neurodegenerative and mental disorders
A Ochneva, Y Zorkina, O Abramova, O Pavlova… - International journal of …, 2022 - mdpi.com
Mental disorders represent common brain diseases characterized by substantial
impairments of social and cognitive functions. The neurobiological causes and mechanisms …
impairments of social and cognitive functions. The neurobiological causes and mechanisms …
[HTML][HTML] N, N-dimethyltryptamine compound found in the hallucinogenic tea ayahuasca, regulates adult neurogenesis in vitro and in vivo
JA Morales-Garcia, J Calleja-Conde… - Translational …, 2020 - nature.com
Abstract N, N-dimethyltryptamine (DMT) is a component of the ayahuasca brew traditionally
used for ritual and therapeutic purposes across several South American countries. Here, we …
used for ritual and therapeutic purposes across several South American countries. Here, we …
[HTML][HTML] Revisiting the sigma-1 receptor as a biological target to treat affective and cognitive disorders
K Sałaciak, K Pytka - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Depression and cognitive disorders are diseases with complex and not-fully understood
etiology. Unfortunately, the COVID-19 pandemic dramatically increased the prevalence of …
etiology. Unfortunately, the COVID-19 pandemic dramatically increased the prevalence of …
[HTML][HTML] Sigma-1 receptors in depression: mechanism and therapeutic development
P Ren, J Wang, N Li, G Li, H Ma, Y Zhao… - Frontiers in …, 2022 - frontiersin.org
Depression is the most common type of neuropsychiatric illness and has increasingly
become a major cause of disability. Unfortunately, the recent global pandemic of COVID-19 …
become a major cause of disability. Unfortunately, the recent global pandemic of COVID-19 …
[HTML][HTML] The calcium/calmodulin-dependent kinases II and IV as therapeutic targets in neurodegenerative and neuropsychiatric disorders
K Sałaciak, A Koszałka, E Żmudzka… - International Journal of …, 2021 - mdpi.com
CaMKII and CaMKIV are calcium/calmodulin-dependent kinases playing a rudimentary role
in many regulatory processes in the organism. These kinases attract increasing interest due …
in many regulatory processes in the organism. These kinases attract increasing interest due …
[HTML][HTML] Acute effects of ayahuasca in a juvenile non-human primate model of depression
Objective: The incidence rate of major depression in adolescents reaches approximately
14%. This disorder is usually recurrent, without remission of symptoms even after …
14%. This disorder is usually recurrent, without remission of symptoms even after …
Neuroinflammation and aberrant hippocampal plasticity in a mouse model of emotional stress evoked by exposure to ultrasound of alternating frequencies
Emotional stress is a form of stress evoked by processing negative mental experience rather
than an organic or physical disturbance and is a frequent cause of neuropsychiatric …
than an organic or physical disturbance and is a frequent cause of neuropsychiatric …
[HTML][HTML] Chaperone Sigma1R and antidepressant effect
MV Voronin, YV Vakhitova, SB Seredenin - International Journal of …, 2020 - mdpi.com
This review analyzes the current scientific literature on the role of the Sigma1R chaperone in
the pathogenesis of depressive disorders and pharmacodynamics of antidepressants. As a …
the pathogenesis of depressive disorders and pharmacodynamics of antidepressants. As a …
Sigma-1 receptor: A potential target for the development of antidepressants
YM Wang, CY Xia, HM Jia, J He, WW Lian… - Neurochemistry …, 2022 - Elsevier
Though a great many of studies on the development of antidepressants for the therapy of
major depression disorder (MDD) and the development of antidepressants have been …
major depression disorder (MDD) and the development of antidepressants have been …