There is increasing recognition in the neurological and psychiatric literature of patients with
so-called isolated psychotic presentations (ie, with no, or minimal, neurological features) …

This paper discusses the current evidence from animal and human studies for a central role
of inflammation in schizophrenia. In animal models, pre-or perinatal elicitation of the immune …

Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of
alleles, including common alleles of small effect that might be detected by genome-wide …

Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of
alleles, including common alleles of small effect that might be detected by genome-wide …

High levels of pro-inflammatory substances such as cytokines have been described in the
blood and cerebrospinal fluid of schizophrenia patients. Animal models of schizophrenia …

Associations between influenza infection and psychosis have been reported since the
eighteenth century, with acute “psychoses of influenza” documented during multiple …

BackgroundAccumulating evidence shows that a propensity towards a pro-inflammatory
status in the brain plays an important role in schizophrenia. Anti-inflammatory drugs might …

Blood–brain barrier pathology is recognised as a central factor in the development of many
neurological disorders, but much less is known about the role of the blood–brain barrier in …

Humans evolved within a microbial ecosystem resulting in an interlinked physiology. The gut
microbiota can signal to the brain via the immune system, the vagus nerve or other host …

Schizophrenia and bipolar disorder are serious neuropsychiatric disorders of uncertain
etiology. Recent studies indicate that immune activation may contribute to the …