Blood pressure variability and plasma Alzheimer's disease biomarkers in the SPRINT trial

IJ Sible, DA Nation - Journal of Alzheimer's Disease, 2024 - content.iospress.com
Background: Recent observational studies suggest higher blood pressure (BP) variability
(BPV) is associated with Alzheimer's disease (AD) biomarkers amyloid-beta (Aβ) and tau …

[HTML][HTML] The Impact of Hypertension on Cognitive Decline and Alzheimer's Disease and Its Management: A Systematic Review

AD Khan, S Elnagar, M Eltayeb, SK Baluch, A Kumar… - Cureus, 2024 - ncbi.nlm.nih.gov
Hypertension, a major risk factor for cardiovascular diseases, has also been linked to
cognitive decline and Alzheimer's disease (AD). This systematic review synthesizes the …

Long‐Term Visit‐to‐Visit Blood Pressure Variability and Cognitive Decline Among Patients With Hypertension: A Pooled Analysis of 3 National Prospective Cohorts

G Zheng, B Zhou, Z Fang, X Chen, M Liu… - Journal of the …, 2024 - ahajournals.org
Background A limited number of studies investigated the association between blood
pressure variability (BPV) and cognitive impairment in patients with hypertension. This study …

[HTML][HTML] 24-Hour Blood Pressure Variability Via Ambulatory Monitoring and Risk for Probable Dementia in the SPRINT Trial

IJ Sible, DA Nation - The Journal of Prevention of Alzheimer's Disease, 2024 - Springer
Background Blood pressure variability is an emerging risk factor for dementia, independent
and oftentimes beyond mean blood pressure levels. Recent evidence from interventional …

[HTML][HTML] Short-term blood pressure variability is inversely related to regional amplitude of low frequency fluctuations in older and younger adults

IJ Sible, HJ Yoo, J Min, K Nashiro, C Chang, DA Nation… - Aging Brain, 2023 - Elsevier
Blood pressure variability (BPV), independent of mean blood pressure levels, is associated
with cerebrovascular disease burden on MRI and postmortem evaluation. However, less is …

The interactive effect of intra-beat and inter-beat blood pressure variability on neurodegeneration in older adults

T Lohman, F Shenasa, IJ Sible, A Kapoor… - medRxiv, 2024 - medrxiv.org
Blood pressure variability (BPV) and arterial stiffness are age-related hemodynamic risk
factors for neurodegenerative disease, but it remains unclear whether they exert …

[HTML][HTML] Reliability of beat-to-beat blood pressure variability in older adults

T Lohman, IJ Sible, F Shenasa, AC Engstrom… - Research …, 2024 - ncbi.nlm.nih.gov
Blood pressure variability (BPV) is emerging as an important risk factor across numerous
disease states, including cerebrovascular and neurodegenerative disease in older adults …

[HTML][HTML] Association of longitudinal changes in 24-h blood pressure level and variability with cognitive decline

JD Melgarejo, KP Vatcheva, S Mejia-Arango… - Journal of …, 2024 - journals.lww.com
Objective: A high office blood pressure (BP) is associated with cognitive decline. However,
evidence of 24-h ambulatory BP monitoring is limited, and no studies have investigated …