Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

The prevalence of osteoarthritis (OA) and the burden associated with the disease are
steadily increasing worldwide, representing a major public health challenge for the coming …

Osteoarthritis (OA) is a degenerative joint disorder commonly encountered in clinical
practice, and is the leading cause of disability in elderly people. Due to the poor self-healing …

Background: Knee osteoarthritis (KOA) is one of the most common chronic musculoskeletal
disorders worldwide, for which exosomes derived from stem cells may provide an effective …

Cartilage and the bordering subchondral bone form a functionally active regulatory interface
with a prominent role in osteoarthritis pathways. The Wnt and the OPG-RANKL-RANK …

Objective To investigate the impact of systemic inhibition of interleukin 6 (IL-6) or signal
transducer and activator of transcription (Stat3) in an experimental model of osteoarthritis …

Osteoarthritis (OA) is the most common joint disease worldwide and a leading cause of
disability. Characterized by degradation of articular cartilage, synovial inflammation, and …

Increased vascular endothelial growth factor (VEGF) levels are associated with osteoarthritis
(OA) progression. Indeed, VEGF appears to be involved in OA‐specific pathologies …

Cartilage not only plays essential roles in skeletal development and growth during pre-and
postnatal stages but also serves to provide smooth movement of skeletons throughout life …

There is emerging awareness that subchondral bone remodeling plays an important role in
the development of osteoarthritis (OA). This review presents recent investigations on the …