Depression as a spreading adjustment disorder of monoaminergic neurons: a case for primary implication of the locus coeruleus
J Harro, L Oreland - Brain Research Reviews, 2001 - Elsevier
A model for the pathophysiology of depression is discussed in the context of other existing
theories. The classic monoamine theory of depression suggests that a deficit in monoamine …
theories. The classic monoamine theory of depression suggests that a deficit in monoamine …
Metabolomics study on the anti-depression effect of xiaoyaosan on rat model of chronic unpredictable mild stress
Y Dai, Z Li, L Xue, C Dou, Y Zhou, L Zhang… - Journal of …, 2010 - Elsevier
ETHNOPHARMACOLOGY: Xiaoyaosan, a famous Chinese prescription, composed of Poria
(Poria cocos (Schw.) Wolf), Radix Paeoniae Alba (Paeonia lactiflora Pall.), Radix …
(Poria cocos (Schw.) Wolf), Radix Paeoniae Alba (Paeonia lactiflora Pall.), Radix …
Chronic mild stress generates clear depressive but ambiguous anxiety-like behaviour in rats
A 3-week chronic mild stress (CMS) protocol decreased sucrose preference of rats and
increased immobility in the forced swim test. It also induced social avoidance and increased …
increased immobility in the forced swim test. It also induced social avoidance and increased …
Effect of chronic unpredictable mild stress on brain–pancreas relative protein in rat brain and pancreas
YH Lin, AH Liu, Y Xu, L Tie, HM Yu, XJ Li - Behavioural brain research, 2005 - Elsevier
Brain–pancreas relative protein (BPRP) is a novel protein whose biological function remains
unknown. Here, we report a possible role of BPRP in male rats exposed to chronic …
unknown. Here, we report a possible role of BPRP in male rats exposed to chronic …
Strain and gender specific effects in the forced swim test: effects of previous stress exposure
C Bielajew, ATM Konkle, AC Kentner, SL Baker… - Stress, 2003 - Taylor & Francis
The chronic mild stress (CMS) procedure was developed in rodents to target anhedonia, the
core symptom of depressive melancholia. Stress exposure has been shown to induce a …
core symptom of depressive melancholia. Stress exposure has been shown to induce a …
The effects of chronic mild stress on male Sprague–Dawley and Long Evans rats: I. Biochemical and physiological analyses
C Bielajew, ATM Konkle, Z Merali - Behavioural brain research, 2002 - Elsevier
The chronic unpredictable mild stress (CMS) is a paradigm developed in animals to model
the relatively minor and unanticipated irritants that lead to a state of anhedonia in some …
the relatively minor and unanticipated irritants that lead to a state of anhedonia in some …
Antidepressant effect of Chaihu-Shugan-San extract and its constituents in rat models of depression
SH Kim, J Han, DH Seog, JY Chung, N Kim, YH Park… - Life sciences, 2005 - Elsevier
Herbal preparations may be effective alternatives in the treatment of depression, which
remains difficult to manage. Chaihu-Shugan-San (CSS), an oriental traditional medicine …
remains difficult to manage. Chaihu-Shugan-San (CSS), an oriental traditional medicine …
Nicotine significantly improves chronic stress-induced impairments of cognition and synaptic plasticity in mice
X Shang, Y Shang, J Fu, T Zhang - Molecular neurobiology, 2017 - Springer
The aim of this study was to examine if nicotine was able to improve cognition deficits in a
mouse model of chronic mild stress. Twenty-four male C57BL/6 mice were divided into three …
mouse model of chronic mild stress. Twenty-four male C57BL/6 mice were divided into three …
Chronic variable stress and partial 5-HT denervation by parachloroamphetamine treatment in the rat: effects on behavior and monoamine neurochemistry
J Harro, M Tõnissaar, M Eller, A Kask, L Oreland - Brain research, 2001 - Elsevier
Chronic variable stress (CVS) and manipulations of 5-HT-ergic neurotransmission are
increasingly used as animal models of depression. In the present study, CVS for 2 weeks …
increasingly used as animal models of depression. In the present study, CVS for 2 weeks …
Effects of Rhodiola rosea L. extract on behavioural and physiological alterations induced by chronic mild stress in female rats
L Mattioli, C Funari, M Perfumi - Journal of …, 2009 - journals.sagepub.com
Rhodiola rosea L. is one of the most popular adaptogen and an antistress plant in European
and Asiatic traditional medicine. Our previous studies have confirmed the adaptogenic and …
and Asiatic traditional medicine. Our previous studies have confirmed the adaptogenic and …