Is DNA methylation in the brain a mechanism of alcohol use disorder?
J Jarczak, M Miszczak, K Radwanska - Frontiers in Behavioral …, 2023 - frontiersin.org
Alcohol use disorder (AUD) is a worldwide problem. Unfortunately, the molecular
mechanisms of alcohol misuse are still poorly understood, therefore successful therapeutic …
mechanisms of alcohol misuse are still poorly understood, therefore successful therapeutic …
Adolescent binge ethanol impacts H3K36me3 regulation of synaptic genes
ER Brocato, JT Wolstenholme - Frontiers in Molecular Neuroscience, 2023 - frontiersin.org
Adolescence is marked in part by the ongoing development of the prefrontal cortex (PFC).
Binge ethanol use during this critical stage in neurodevelopment induces significant …
Binge ethanol use during this critical stage in neurodevelopment induces significant …
Molecular aspects of hypoxic stress effects in Chronic ethanol exposure of neuronal cells
Experimental models of a clinical, pathophysiological context are used to understand
molecular mechanisms and develop novel therapies. Previous studies revealed better …
molecular mechanisms and develop novel therapies. Previous studies revealed better …
Gut–liver highway of ALDH2 in drinking
SC Pandey, E Malovic - Nature Metabolism, 2024 - nature.com
Gut–liver highway of ALDH2 in drinking | Nature Metabolism Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …
Methamphetamine-induced region-specific transcriptomic and epigenetic changes in the brain of male rats
B Miao, X Xing, V Bazylianska, P Madden… - Communications …, 2023 - nature.com
Psychostimulant methamphetamine (METH) is neurotoxic to the brain and, therefore, its
misuse leads to neurological and psychiatric disorders. The gene regulatory network (GRN) …
misuse leads to neurological and psychiatric disorders. The gene regulatory network (GRN) …
Genetic factors associated with suicidal behaviors and alcohol use disorders in an American Indian population
Q Peng, DA Gilder, RA Bernert, KJ Karriker-Jaffe… - Molecular …, 2024 - nature.com
American Indians (AI) demonstrate the highest rates of both suicidal behaviors (SB) and
alcohol use disorders (AUD) among all ethnic groups in the US. Rates of suicide and AUD …
alcohol use disorders (AUD) among all ethnic groups in the US. Rates of suicide and AUD …
Activation/inhibition of gene expression caused by alcohols: Relationship with the viscoelastic property of a DNA molecule
K Fujino, T Nishio, K Fujioka, Y Yoshikawa… - Polymers, 2022 - mdpi.com
Alcohols are used in the life sciences because they can condense and precipitate DNA.
Alcohol consumption has been linked to many diseases and can alter genetic activity. In the …
Alcohol consumption has been linked to many diseases and can alter genetic activity. In the …
Could nutrition status predict fatigue one week before in patients with nasopharynx cancer undergoing radiotherapy?
J Song, X Yang, J Wu, Z Wu, L Zhuo, J Hong… - Cancer …, 2024 - Wiley Online Library
Background Patients with nasopharyngeal carcinoma (NPC) undergoing radiotherapy
experience significant fatigue, which is frequently underestimated due to the lack of …
experience significant fatigue, which is frequently underestimated due to the lack of …
Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder
N Green, H Gao, X Chu, Q Yuan, P McGuire, D Lai… - bioRxiv, 2024 - biorxiv.org
Alcohol use disorder (AUD) is likely associated with complex transcriptional alterations in
addiction-relevant brain regions. We characterize AUD-associated differences in cell type …
addiction-relevant brain regions. We characterize AUD-associated differences in cell type …
Environmental factors and epigenetics of neuropsychiatric disorders
J Peedicayil - Neuropsychiatric Disorders and Epigenetics, 2024 - Elsevier
Brain development is highly plastic due to rapid changes in cell numbers and neural
connectivity that together allow the integration of a broad scope of intrinsic and …
connectivity that together allow the integration of a broad scope of intrinsic and …