Alcohol use disorder (AUD) is a worldwide problem. Unfortunately, the molecular
mechanisms of alcohol misuse are still poorly understood, therefore successful therapeutic …

Adolescence is marked in part by the ongoing development of the prefrontal cortex (PFC).
Binge ethanol use during this critical stage in neurodevelopment induces significant …

Experimental models of a clinical, pathophysiological context are used to understand
molecular mechanisms and develop novel therapies. Previous studies revealed better …

Gut–liver highway of ALDH2 in drinking | Nature Metabolism Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

Psychostimulant methamphetamine (METH) is neurotoxic to the brain and, therefore, its
misuse leads to neurological and psychiatric disorders. The gene regulatory network (GRN) …

American Indians (AI) demonstrate the highest rates of both suicidal behaviors (SB) and
alcohol use disorders (AUD) among all ethnic groups in the US. Rates of suicide and AUD …

Alcohols are used in the life sciences because they can condense and precipitate DNA.
Alcohol consumption has been linked to many diseases and can alter genetic activity. In the …

Background Patients with nasopharyngeal carcinoma (NPC) undergoing radiotherapy
experience significant fatigue, which is frequently underestimated due to the lack of …

Alcohol use disorder (AUD) is likely associated with complex transcriptional alterations in
addiction-relevant brain regions. We characterize AUD-associated differences in cell type …

Brain development is highly plastic due to rapid changes in cell numbers and neural
connectivity that together allow the integration of a broad scope of intrinsic and …