CircRNA_0058063 functions as a ceRNA in bladder cancer progression via targeting miR-486-3p/FOXP4 axis

H Liang, H Huang, Y Li, Y Lu, T Ye - Bioscience Reports, 2020 - portlandpress.com
Emerging evidence has uncovered critical regulatory roles of circular RNAs (circRNAs)
function as dynamic scaffolding molecules in tumorigenesis and progression. However, the …

Integrating germline and somatic variation information using genomic data for the discovery of biomarkers in prostate cancer

TKK Mamidi, J Wu, C Hicks - BMC cancer, 2019 - Springer
Abstract Background Prostate cancer (PCa) is the most common diagnosed malignancy and
the second leading cause of cancer-related deaths among men in the United States. High …

Interactions between germline and somatic mutated genes in aggressive prostate cancer

TKK Mamidi, J Wu, C Hicks - Prostate Cancer, 2019 - Wiley Online Library
Prostate cancer (PCa) is the most common diagnosed malignancy and the second leading
cause of cancer‐related deaths among men in the USA. Advances in high‐throughput …

SNPs-Panel Polymorphism Variations in GHRL and GHSR Genes Are Not Associated with Prostate Cancer

N Merabet, N Ramoz, A Boulmaiz, A Bourefis… - Biomedicines, 2023 - mdpi.com
Prostate cancer (PCa) is a major public health problem worldwide. Recent studies have
suggested that ghrelin and its receptor could be involved in the susceptibility to several …

Mapping the germline and somatic mutation interaction landscape in indolent and aggressive prostate cancers

TKK Mamidi, J Wu, C Hicks - Journal of Oncology, 2019 - Wiley Online Library
Background. A majority of prostate cancers (PCas) are indolent and cause no harm even
without treatment. However, a significant proportion of patients with PCa have aggressive …

Integrative genomic analysis for the discovery of biomarkers in prostate cancer

C Hicks, T Koganti, S Giri, M Tekere… - Biomarker …, 2014 - journals.sagepub.com
Genome-wide association studies (GWAS) have achieved great success in identifying single
nucleotide polymorphisms (SNPs, herein called genetic variants) and genes associated with …

Enriching gene expression profiles will help personalize prostate cancer management for African-Americans: a perspective

S Vijayakumar, JC Henegan, X Zhang, W Wang… - … Oncology: Seminars and …, 2017 - Elsevier
Prostate cancer (PCa) remains the most common form of cancer affecting men in the
Western Hemisphere. Mortality rate is 130% higher among African-American men (AAM) …

Elucidation of the Genomic‐Epigenomic Interaction Landscape of Aggressive Prostate Cancer

TK Kumar Mamidi, J Wu, C Hicks - BioMed research …, 2021 - Wiley Online Library
Background. Majority of prostate cancer (PCa) deaths are attributed to localized high‐grade
aggressive tumours which progress rapidly to metastatic disease. A critical unmet need in …

An integrative genomics approach for associating genome-wide association studies information with localized and metastatic prostate cancer phenotypes

C Hicks, R Ramani, O Sartor, R Bhalla… - Biomarker …, 2017 - journals.sagepub.com
High-throughput genotyping has enabled discovery of genetic variants associated with an
increased risk of developing prostate cancer using genome-wide association studies …

Identification of the genetic alterations in prostate cancer metastases

E Stankiewicz - 2017 - qmro.qmul.ac.uk
Prostate cancer (PCa) is the most common cancer among men in Western developed
countries. While the majority of PCa diagnosed by PSA screening are indolent, advanced …