Breast cancer is a severe problem worldwide due to an increase in mortality and prevalence
among women. Despite early diagnostic procedures as well as advanced therapies, more …

Cancer immunotherapy moderates the immune system's ability to fight cancer. Due to its
extreme complexity, scientists are working to put together all the puzzle pieces to get a …

Background and aims CCL5 is considered to contribute to the biological function of a variety
of cancer types, but its specific mechanism is still unclear. This study aimed to reveal the …

Prostate cancer is one of the most common malignant tumors in men. Initially, it is androgen-
dependent, but it eventually develops into castration-resistant prostate cancer (CRPC) …

Phytochemicals are natural plant-derived products that provide significant nutrition, essential
biomolecules, and flavor as part of our diet. They have long been known to confer protection …

In various pathological conditions, cellular immunity plays an important role in immune
responses. Among immune cells, T lymphocytes pdomote cellular and humoral responses …

Chemotherapy drugs are still one of the first treatment options used in many cancers;
however, problems such as cytotoxic side effects on normal cells after systemic …

Prostate cancer (PC) is the most common type of tumor in men. In the early stage of the
disease, it is sensitive to androgen deprivation therapy. In patients with metastatic castration …

Background The origin recognition complex (ORC), a six-subunit DNA-binding complex,
participates in DNA replication in cancer cells. Specifically in prostate cancers, ORC …

The distinct tumor microenvironment (TME) of prostate cancer (PCa), which promotes tumor
proliferation and progression, consists of various stromal cells, immune cells, and a dense …