Introduction: Respiratory drug delivery is a surprisingly complex process with a number of
physical and biological challenges. Computational fluid dynamics (CFD) is a scientific …

Effective evaluation and prediction of aerosol transport deposition in the human respiratory
tracts are critical to aerosol drug delivery and evaluation of inhalation products …

Although ambient particulate matter or particles have been found to be associated with
morbidity and mortality all over the world, specific health effects of particles from different …

When the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
emerged in 2019, researchers rapidly recalibrated epidemiological computer models …

Prediction of the air-particle dynamics in human lungs can reveal critical deposition sites of
toxins or can determine best physical parameters for direct drug delivery and associated …

This article reviews recent developments in computational modeling of dry powder inhalers
(DPIs). DPIs deliver drug formulations (sometimes blended with larger carrier particles) to a …

Airflow and aerosol deposition in the human airways are important aspects for applications
such as pulmonary drug delivery and human exposure to aerosol pollutants. Numerical …

Dynamic modeling of how particulate matter (PM) transport, deposit, and translocate from
human respiratory systems to systemic regions subject to indoor and outdoor exposures are …

Most existing whole lung models neglect the airway deformation kinematics and assume the
lung airways are static. However, neglecting the airway deformation effect on pulmonary air …

Studying airflow characteristics in the human respiratory system is important for
understanding the properties of the aerosol transport and deposition. This study first …