Laboratory diagnosis of antiphospholipid syndrome: insights and hindrances

A Vandevelde, KMJ Devreese - Journal of Clinical Medicine, 2022 - mdpi.com
Diagnosis of antiphospholipid syndrome (APS) requires the presence of a clinical criterion
(thrombosis and/or pregnancy morbidity), combined with persistently circulating …

Antiphospholipid antibody assays in 2021: looking for a predictive value in addition to a diagnostic one

PL Meroni, MO Borghi - Frontiers in immunology, 2021 - frontiersin.org
Antiphospholipid antibodies (aPL) are mandatory for the diagnosis but are also a risk factor
for the antiphospholipid syndrome (APS) clinical manifestations. Lupus anticoagulant (LA) …

[HTML][HTML] Antiphospholipid antibodies in patients with COVID‐19: a relevant observation?

KMJ Devreese, EA Linskens, D Benoit… - Journal of Thrombosis …, 2020 - Elsevier
Background High incidence of thrombosis in COVID‐19 patients indicates a
hypercoagulable state. Hence, exploring the involvement of antiphospholipid antibodies …

[HTML][HTML] Semiquantitative interpretation of anticardiolipin and antiβ2glycoprotein I antibodies measured with various analytical platforms: communication from the ISTH …

A Vandevelde, W Chayoua, B de Laat, JC Gris… - Journal of Thrombosis …, 2022 - Elsevier
Background Antiβ2glycoprotein I (aβ2GPI) and anticardiolipin (aCL) IgG/IgM show
differences in positive/negative agreement and titers between solid phase platforms. Method …

[HTML][HTML] Role of antiphospholipid antibodies in the diagnosis of antiphospholipid syndrome

KMJ Devreese, S Zuily, PL Meroni - Journal of Translational Autoimmunity, 2021 - Elsevier
The diagnosis of antiphospholipid syndrome (APS) relies on the detection of
antiphospholipid antibodies (aPL). Currently, lupus anticoagulant (LA), anticardiolipin (aCL) …

Anti-phosphatidylserine/prothrombin antibodies at two points: correlation with lupus anticoagulant and thrombotic risk

N Egri, C Bentow, L Rubio, GL Norman… - Frontiers in …, 2021 - frontiersin.org
Antibodies to phospholipids (aPL) and associated proteins are a hallmark in the diagnosis of
anti-phospholipid syndrome (APS). Those included in the classification criteria are the lupus …

Solid phase assays for antiphospholipid antibodies

KMJ Devreese - Seminars in Thrombosis and Hemostasis, 2022 - thieme-connect.com
The diagnosis of antiphospholipid syndrome (APS) relies on the detection of circulating
antiphospholipid antibodies (aPL). Currently, lupus anticoagulant (LA), anticardiolipin (aCL) …

Current promising biomarkers and methods in the diagnostics of antiphospholipid syndrome: a review

P Bradacova, L Slavik, J Ulehlova, A Skoumalova… - Biomedicines, 2021 - mdpi.com
Antiphospholipid syndrome (APS) is a hypercoagulation condition associated with the
incidence of heterogenic antiphospholipid antibodies (aPLs), which non-specifically affect …

Criteria and Non-Criteria Antiphospholipid Antibodies in Antiphospholipid Syndrome: How Strong Are They Correlated?

S Caraiola, L Voicu, C Jurcut, A Dima, C Baicus… - Biomedicines, 2023 - mdpi.com
The place of non-criteria antiphospholipid antibodies (aPLs) in the diagnosis of
antiphospholipid syndrome (APS) is still debatable. The aim of this research was to evaluate …

Comparison of different test systems for the detection of antiphospholipid antibodies in a Chinese cohort

C Hu, S Li, Z Xie, H You, H Jiang, Y Shi, W Qi… - Frontiers in …, 2021 - frontiersin.org
Background Diagnosis of antiphospholipid syndrome (APS) is based on the positivity of
laboratory criteria antiphospholipid antibodies (aPLs). Test results for aPLs could be …