Small molecule metabolites: discovery of biomarkers and therapeutic targets
S Qiu, Y Cai, H Yao, C Lin, Y Xie, S Tang… - Signal Transduction and …, 2023 - nature.com
Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
The complement system in age-related macular degeneration
Age-related macular degeneration (AMD) is a chronic and progressive degenerative
disease of the retina, which culminates in blindness and affects mainly the elderly …
disease of the retina, which culminates in blindness and affects mainly the elderly …
Age-related macular degeneration
Age-related macular degeneration (AMD) is the leading cause of legal blindness in the
industrialized world. AMD is characterized by accumulation of extracellular deposits, namely …
industrialized world. AMD is characterized by accumulation of extracellular deposits, namely …
Dyslipidemia in age-related macular degeneration
Lipid-rich drusen are the sine qua non of age-related macular degeneration (AMD), the
leading cause of blindness in older adults in the developed world. Efforts directed at …
leading cause of blindness in older adults in the developed world. Efforts directed at …
Pathophysiology of age-related macular degeneration: implications for treatment
J Garcia-Garcia, R Usategui-Martin, MR Sanabria… - Ophthalmic …, 2022 - karger.com
Age-related macular degeneration (AMD) is a complex, multifactorial, progressive retinal
disease that affects millions of people worldwide and has become the leading cause of …
disease that affects millions of people worldwide and has become the leading cause of …
[HTML][HTML] Global, regional, and national burden of blindness and vision loss due to common eye diseases along with its attributable risk factors from 1990 to 2019: a …
X Yang, H Chen, T Zhang, X Yin, J Man, Q He… - Aging (albany …, 2021 - ncbi.nlm.nih.gov
To map the magnitudes and temporal trends of blindness and vision loss (BVL) due to
common eye diseases along with its attributable risk factors at the national, regional, and …
common eye diseases along with its attributable risk factors at the national, regional, and …
Age‐related macular degeneration: A disease of extracellular complement amplification
Age‐related macular degeneration (AMD) is a major cause of vision impairment in the
Western World, and with the aging world population, its incidence is increasing. As of today …
Western World, and with the aging world population, its incidence is increasing. As of today …
Integrating genetics and metabolomics from multi-ethnic and multi-fluid data reveals putative mechanisms for age-related macular degeneration
Age-related macular degeneration (AMD) is a leading cause of blindness in older adults.
Investigating shared genetic components between metabolites and AMD can enhance our …
Investigating shared genetic components between metabolites and AMD can enhance our …
Metabolomics in age-related macular degeneration: a systematic review
XW Hou, Y Wang, CW Pan - Investigative ophthalmology & …, 2020 - iovs.arvojournals.org
Purpose: Age-related macular degeneration (AMD) is one of the leading causes of
blindness among the elderly, and the exact pathogenesis of the AMD remains unclear. The …
blindness among the elderly, and the exact pathogenesis of the AMD remains unclear. The …
New insight of metabolomics in ocular diseases in the context of 3P medicine
Q Zhang, N Wang, Y Rui, Y Xia, S Xiong, X Xia - EPMA Journal, 2023 - Springer
Metabolomics refers to the high-through untargeted or targeted screening of metabolites in
biofluids, cells, and tissues. Metabolome reflects the functional states of cells and organs of …
biofluids, cells, and tissues. Metabolome reflects the functional states of cells and organs of …