Natural history and mechanisms of COPD
P Lange, E Ahmed, ZM Lahmar, FJ Martinez… - …, 2021 - Wiley Online Library
The natural history of COPD is complex, and the disease is best understood as a syndrome
resulting from numerous interacting factors throughout the life cycle with smoking being the …
resulting from numerous interacting factors throughout the life cycle with smoking being the …
Imaging advances in chronic obstructive pulmonary disease. Insights from the genetic epidemiology of chronic obstructive pulmonary disease (COPDGene) study
SP Bhatt, GR Washko, EA Hoffman… - American journal of …, 2019 - atsjournals.org
The Genetic Epidemiology of Chronic Obstructive Pulmonary Disease (COPDGene) study,
which began in 2007, is an ongoing multicenter observational cohort study of more than …
which began in 2007, is an ongoing multicenter observational cohort study of more than …
[HTML][HTML] X-ray dark-field chest imaging for detection and quantification of emphysema in patients with chronic obstructive pulmonary disease: a diagnostic accuracy …
Background Although advanced medical imaging technologies give detailed diagnostic
information, a low-dose, fast, and inexpensive option for early detection of respiratory …
information, a low-dose, fast, and inexpensive option for early detection of respiratory …
Deep learning enables automatic classification of emphysema pattern at CT
SM Humphries, AM Notary, JP Centeno, MJ Strand… - Radiology, 2020 - pubs.rsna.org
Background Pattern of emphysema at chest CT, scored visually by using the Fleischner
Society system, is associated with physiologic impairment and mortality risk. Purpose To …
Society system, is associated with physiologic impairment and mortality risk. Purpose To …
[HTML][HTML] At the root: defining and halting progression of early chronic obstructive pulmonary disease
FJ Martinez, MLK Han, JP Allinson, RG Barr… - American journal of …, 2018 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is a prevalent, heterogeneous disorder with
varying presentation and progression but with a limited number of disease-modifying …
varying presentation and progression but with a limited number of disease-modifying …
Endoscopic lung volume reduction: an expert panel recommendation–update 2019
Endoscopic lung volume reduction (ELVR) therapies are gaining prominence as a treatment
option with guideline recommendations by COPD GOLD and NICE and the recent FDA …
option with guideline recommendations by COPD GOLD and NICE and the recent FDA …
[HTML][HTML] Preserved ratio impaired spirometry is associated with small airway dysfunction and reduced total lung capacity
N Zhao, F Wu, J Peng, Y Zheng, H Tian, H Yang… - Respiratory …, 2022 - Springer
Background: Preserved ratio impaired spirometry (PRISm) refers to decreased forced
expiratory volume in 1 s (FEV1) in the setting of preserved ratio. Little is known about the …
expiratory volume in 1 s (FEV1) in the setting of preserved ratio. Little is known about the …
Causes of and clinical features associated with death in tobacco cigarette users by lung function impairment
Rationale: Cigarette smoking contributes to the risk of death through different mechanisms.
Objectives: To determine how causes of and clinical features associated with death vary in …
Objectives: To determine how causes of and clinical features associated with death vary in …
Quantitative emphysema on low-dose CT imaging of the chest and risk of lung cancer and airflow obstruction: an analysis of the national lung screening trial
Background Lung cancer risk prediction models do not routinely incorporate imaging metrics
available on low-dose CT (LDCT) imaging of the chest ordered for lung cancer screening …
available on low-dose CT (LDCT) imaging of the chest ordered for lung cancer screening …
Emphysema progression at CT by deep learning predicts functional impairment and mortality: results from the COPDGene study
Background Visual assessment remains the standard for evaluating emphysema at CT;
however, it is time consuming, is subjective, requires training, and is affected by variability …
however, it is time consuming, is subjective, requires training, and is affected by variability …