Worsening Heart Failure: Nomenclature, Epidemiology, and Future Directions: JACC Review Topic of the Week

SJ Greene, J Bauersachs, JJ Brugts… - Journal of the American …, 2023 - jacc.org
Heart failure (HF) is a progressive disease characterized by variable durations of
symptomatic stability often punctuated by episodes of worsening despite continued therapy …

[HTML][HTML] Improving the enrollment of women and racially/ethnically diverse populations in cardiovascular clinical trials: an ASPC practice statement

ED Michos, TK Reddy, M Gulati, LPC Brewer… - American Journal of …, 2021 - Elsevier
Cardiovascular disease (CVD) remains the leading cause of death for both women and men
worldwide. In the United States (US), there are significant disparities in cardiovascular risk …

Effect of empagliflozin on worsening heart failure events in patients with heart failure and preserved ejection fraction: EMPEROR-preserved trial

M Packer, J Butler, F Zannad, G Filippatos, JP Ferreira… - Circulation, 2021 - Am Heart Assoc
Background: Empagliflozin reduces the risk of cardiovascular death or hospitalization for
heart failure in patients with heart failure with preserved ejection fraction, but additional data …

Worsening of chronic heart failure: definition, epidemiology, management and prevention. A clinical consensus statement by the Heart Failure Association of the …

M Metra, D Tomasoni, M Adamo… - European Journal of …, 2023 - Wiley Online Library
Episodes of worsening symptoms and signs characterize the clinical course of patients with
chronic heart failure (HF). These events are associated with poorer quality of life, increased …

Hospital at home as a treatment strategy for worsening heart failure

HB Haywood, GC Fonarow, MS Khan… - Circulation: Heart …, 2023 - Am Heart Assoc
Hospital at home (HaH) is an innovative care model that may be particularly suited for heart
failure (HF). Outpatient visits and inpatient care have been the 2 traditional settings for HF …

Potential implications of expanded US Food and Drug Administration labeling for sacubitril/valsartan in the US

M Vaduganathan, BL Claggett, SJ Greene… - JAMA …, 2021 - jamanetwork.com
Importance The US Food and Drug Administration (FDA) expanded labeling for
sacubitril/valsartan for use in individuals with chronic heart failure (HF) with left ventricular …

Outpatient worsening among patients with mildly reduced and preserved ejection fraction heart failure in the DELIVER trial

S Chatur, M Vaduganathan, BL Claggett… - Circulation, 2023 - Am Heart Assoc
BACKGROUND: Hospitalization is recognized as a sentinel event in the disease trajectory of
patients with heart failure (HF), but not all patients experiencing clinical decompensation are …

Effect of dapagliflozin on total heart failure events in patients with heart failure with mildly reduced or preserved ejection fraction: a prespecified analysis of the …

PS Jhund, BL Claggett, A Talebi, JH Butt… - JAMA …, 2023 - jamanetwork.com
Importance In the Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved
Ejection Fraction Heart Failure (DELIVER) trial, dapagliflozin reduced the risk of time to first …

Neighborhood socioeconomic disadvantage and hospitalized heart failure outcomes in the American Heart Association Get With The Guidelines-Heart Failure registry

VN Rao, RJ Mentz, AC Coniglio, MD Kelsey… - Circulation: Heart …, 2022 - Am Heart Assoc
Background: Neighborhood socioeconomic status (SES) is associated with worse health
outcomes, yet its relationship with in-hospital heart failure (HF) outcomes and quality metrics …

Heart failure with preserved left ventricular ejection fraction: a complex conundrum simply not limited to diastolic dysfunction

A Lopez-Candales, T Asif, K Sawalha… - Cardiovascular …, 2023 - Wiley Online Library
Over the last two decades, the changing paradigm of heart failure with preserved ejection
fraction (HFpEF) has transformed our understanding not only of the pathophysiology of this …